nAChR agonist 1(DUN71755)

Published date: 2022-11-29 15:44:27
nAChR agonist 1(DUN71755) Structure
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Name nAChR agonist 1 CAS# 1394371-75-5
Price ￥Inquiry/1g Purity 98.9%
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Period		 1 Day Stock In Stock
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nAChR agonist 1 is a potent, brain-permeable, and orally efficacious positive allosteric modulator of α7 nicotinic acetylcholine receptor (α7 nAChR). nAChR agonist 1 has the EC50 of 0.32 µM in a Ca2+ mobilization assay (PNU-282987-induced, FLIPR based) in human IMR-32 neuroblastoma cells that endogenously express α7 nAChR. nAChR agonist 1 can be develpoped for the treatment of Alzheimer’s disease.
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