ON-01910

Modify Date: 2025-08-20 10:17:58

ON-01910 structure	Common Name	ON-01910
	CAS Number	1225497-78-8	Molecular Weight	473.47
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₄NNaO₈S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ON-01910

Rigosertib (ON-01910) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Name	Rigosertib
Synonym	More Synonyms

Description	Rigosertib (ON-01910) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others Signaling Pathways >> Cell Cycle/DNA Damage >> Polo-like Kinase (PLK)
Target	PLK1
In Vitro	Rigosertib (ON-01910) sodium 是一种非 ATP 竞争性 PLK1 抑制剂，IC50 为 9 nM，比 Plk2 选择性高 30 倍，对 Plk3 没有抑制活性。
References	[1]. Gumireddy K, et al. ON01910, a non-ATP-competitive small molecule inhibitor of Plk1, is a potent anticancer agent. Cancer Cell. 2005 Mar;7(3):275-86.

Molecular Formula	C₂₁H₂₄NNaO₈S
Molecular Weight	473.47
Exact Mass	473.112030
PSA	131.60000
LogP	2.62230
Storage condition	-20℃

Name: Antiproliferative activity against human A2780 cells measured after 72 hrs by MTT ass...
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL3868217

Name: Antiproliferative activity against human HCT116 cells measured after 72 hrs by MTT as...
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL3868218

Name: Toxicity against NCR-nu/nu, Taconic mouse xenografted with human BT20 cells assessed ...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL2015625

Name: Antitumor activity in human BT20 cells xenografted in NCR-nu/nu, Taconic mouse assess...
Source: ChEMBL
Target: BT-20
External Id: CHEMBL2015624

Name: Resistance ratio of IC50 for human CEM cells to IC50 for multidrug-resistant human CE...
Source: ChEMBL
Target: CEM/C2
External Id: CHEMBL2015627

Name: Aqueous solubility of the compound
Source: ChEMBL
Target: N/A
External Id: CHEMBL2015628

Name: Cytotoxicity against human K562 cells after 96 hrs by trypan blue exclusion assay
Source: ChEMBL
Target: K562
External Id: CHEMBL2015384

Name: Cell cycle arrest in human DU145 cells assessed as accumulation of cells in G2/M phas...
Source: ChEMBL
Target: DU-145
External Id: CHEMBL2015617

Name: Cell cycle arrest in human HFL1 cells assessed as accumulation of cells in G2/M phase...
Source: ChEMBL
Target: HFL1
External Id: CHEMBL2015544

Name: Cell cycle arrest in human DU145 cells assessed as accumulation of cells containing s...
Source: ChEMBL
Target: DU-145
External Id: CHEMBL2015619

Total 42, Current Page 1 of 5

Glycine, N-[2-methoxy-5-[[[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]phenyl]-, sodium salt (1:1)

Sodium {[2-methoxy-5-({[2-(2,4,6-trimethoxyphenyl)vinyl]sulfonyl}methyl)phenyl]amino}acetate

ON-01910

Estybon

Sodium {[2-methoxy-5-({[(E)-2-(2,4,6-trimethoxyphenyl)vinyl]sulfo nyl}methyl)phenyl]amino}acetate

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: ON-01910
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Get all suppliers and price by the below link:

ON-01910 suppliers

ON-01910 price

ON-01910

Use of ON-01910

Names

ON-01910 Biological Activity

Chemical & Physical Properties

ON-01910Bioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.