5-BROMO-2',3',5'-TRI-O-ACETYLURIDINE

Modify Date: 2026-08-02 12:21:25

5-BROMO-2',3',5'-TRI-O-ACETYLURIDINE Structure
5-BROMO-2',3',5'-TRI-O-ACETYLURIDINE structure
Common Name 5-BROMO-2',3',5'-TRI-O-ACETYLURIDINE
CAS Number 105659-32-3 Molecular Weight 449.21
Density 1.66g/cm3 Boiling Point N/A
Molecular Formula C15H17BrN2O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5-BROMO-2',3',5'-TRI-O-ACETYLURIDINE


5-Bromo-2',3',5'-tri-O-acetyluridine diacetate is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 5-Bromo-2',3',5'-tri-O-acetyluridine
Synonym More Synonyms

 5-BROMO-2',3',5'-TRI-O-ACETYLURIDINE Biological Activity

Description 5-Bromo-2',3',5'-tri-O-acetyluridine diacetate is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.66g/cm3
Molecular Formula C15H17BrN2O9
Molecular Weight 449.21
Exact Mass 448.01200
PSA 142.99000
Index of Refraction 1.578
InChIKey OVWGEZUVGHETAU-HKUMRIAESA-N
SMILES CC(=O)OCC1OC(n2cc(Br)c(=O)[nH]c2=O)C(OC(C)=O)C1OC(C)=O

 Synonyms

[3,4-diacetyloxy-5-(5-bromo-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl acetate
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