J. Proteome Res. 14 , 3912-23, (2015)

2015-09-04

Laser microdissection (LMD) was utilized for the separation of the yolk, follicular wall (granulosa and theca), and surrounding stromal cells of small white follicles (SWF) obtained from reproductively active domestic fowl. Herein, we provide an in situ prote...

J. Proteome Res. 14 , 3693-709, (2015)

2015-09-04

Finding protein evidence (PE) for protein coding genes is a primary task of the Phase I Chromosome-Centric Human Proteome Project (C-HPP). Currently, there are 2948 PE level 2-4 coding genes per neXtProt, which are deemed missing proteins in the human proteom...

J. Proteome Res. 14 , 3982-95, (2015)

2015-09-04

"Dry eye" is a multifactorial inflammatory disease affecting the ocular surface. Tear hyperosmolarity in dry eye contributes to inflammation and cell damage. Recent research efforts on dry eye have been directed toward biomarker discovery for diagnosis, respo...

J. Proteome Res. 14 , 3900-11, (2015)

2015-09-04

Besides their role as powerhouses, mitochondria play a pivotal role in the spatial organization of numerous enzymatic functions. They are connected to the ER, and many pathways are organized through the mitochondrial membranes. Thus, the precise definition of...

J. Proteome Res. 14 , 3932-9, (2015)

2015-09-04

Bone marrow-derived human mesenchymal stem cells (BM-hMSCs) have the innate ability to migrate or home toward and engraft in tumors such as glioblastoma (GBM). Because of this unique property of BM-hMSCs, we have explored their use for cell-mediated therapeut...

J. Proteome Res. 14 , 4087-98, (2015)

2015-09-04

Cytokinesis is the last step of the cell cycle that requires coordinated activities of the microtubule cytoskeleton, actin cytoskeleton, and membrane compartments. Aurora B kinase is one of the master regulatory kinases that orchestrate multiple events during...

J. Proteome Res. 14 , 3362-71, (2015)

2015-08-07

Plants increase their root surface with root hairs to improve the acquisition of nutrients from the soil. The unicellular character of root hairs and their position at the root surface make them an attractive system to investigate adaptive processes of rhizod...

J. Proteome Res. 14 , 3051-67, (2015)

2015-08-07

Chlamydomonas reinhardtii was batch-cultured for 12 days under continuous illumination to investigate nitrogen uptake and metabolic responses to wastewater processing. Our approach compared two conditions: (1) artificial wastewater containing nitrate and ammo...

J. Proteome Res. 14 , 3252-62, (2015)

2015-08-07

Histone post-translational modifications (PTMs) are important regulators of chromatin structure and gene expression. Quantitative analysis of histone PTMs by mass spectrometry remains extremely challenging due to the complex and combinatorial nature of histon...

J. Proteome Res. 14 , 3007-14, (2015)

2015-08-07

Solid-pseudopapillary neoplasm (SPN) is an uncommon pancreatic tumor with mutation in CTNNB1 and distinct clinical and pathological features. We compared the proteomic profiles of SPN to mRNA expression. Pooled SPNs and pooled non-neoplastic pancreatic tissue...