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Tetrahydrocurcumin ameliorates free fatty acid-induced hepatic steatosis and improves insulin resistance in HepG2 cells
10.1016/j.jfda.2018.01.005 2018-02-02 Elevated levels of free fatty acids (FFAs) in the liver, resulting from either increased lipolysis or imbalanced FFAs flux, is a key pathogenic factor of hepatic steatosis. This study was conducted to examine the therapeutic effect of tetrahydrocurcumin (THC)... |
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Mulberry leaf extract inhibit hepatocellular carcinoma cell proliferation via depressing IL-6 and TNF-α derived from adipocyte
10.1016/j.jfda.2017.12.007 2018-02-01 Epidemiological studies have revealed that obesity and being overweight are associated with increased cancer risk. Adipose tissue is regarded as an endocrine organ that secretes proinflammatory cytokines such as tumor necrosis factor-α (TNF-α) and interleukin... |
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Elemental profile and oxygen isotope ratio (δ18O) for verifying the geographical origin of Chinese wines
10.1016/j.jfda.2017.12.009 2018-01-18 The elemental profile and oxygen isotope ratio (δ18O) of 188 wine samples collected from the Changji, Mile, and Changli regions in China were analyzed by inductively coupled plasma mass spectrometry (ICP-MS), inductively coupled plasma optical emission spectr... |
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Comparative study of two different chromatographic approaches for quantitation of hydrocortisone acetate and pramoxine hydrochloride in presence of their impurities
10.1016/j.jfda.2017.12.008 2018-01-17 In the present study, we compare the performance of two reversed-phase liquid chromatographic approaches using different eluents either conventional hydro-organic eluent or micellar one for the simultaneous estimation of hydrocortisone acetate and pramoxine h... |
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Effect of Phyllanthus emblica L. fruit on methionine and choline-deficiency diet-induced nonalcoholic steatohepatitis
10.1016/j.jfda.2017.12.005 2018-01-17 Phyllanthus emblica L. fruit contains abundant bioactive components and exhibits a variety of biological activities. In this study, the hepatoprotective effect of water extract of P. emblica (WEPE) on nonalcoholic steatohepatitis (NASH) was evaluated. C57BL/6... |
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Risk undermined in the bilateral pharmaceutical regulatory system in Taiwan
10.1016/j.jfda.2017.11.012 2018-01-17 The concept of Pharmacovigilance Planning and Risk Minimization Planning (PVP/RMP), initiated by the International Conference on Harmonization (ICH), addressed an important conceptual change from monitoring the safety of individual medicine to proactively con... |
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Improvement of nutritional components and in vitro antioxidative properties of soy-powder yogurts using Lactobacillus plantarum
10.1016/j.jfda.2017.12.003 2018-01-17 This research was the first to demonstrate changes in nutritional compositions (isoflavone and CLA) from the 50% methanol extracts of soy-powder milk (SPM) and soy-powder yogurt (SPY) through fermentation using Lactobacillus plantarum S48 and P1201 strains. T... |
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Application of thermal stability difference to remove flammutoxin in fungal immunomodulatory protein FIP-fve extract from Flammulina velutipes
10.1016/j.jfda.2017.12.010 2018-01-17 Fungal immunomodulatory protein (FIP-fve) is a potential functional food ingredient. However, undesirable component flammutoxin (FTX) would occur in the extracted fraction of FIP-fve. In this paper, an application of heating processing instead of the intensiv... |
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Concentrations of perfluoroalkyl substances in foods and the dietary exposure among Taiwan general population and pregnant women
10.1016/j.jfda.2017.12.011 2018-01-17 This study quantified five perfluorocarboxylic acids (PFCAs) and two perfluorosulfonic acids in cereals, meats, seafood, eggs, pork liver, and milk in Taiwan using ultra-performance liquid chromatography-tandem mass spectrometry and evaluated the dietary expo... |
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A feasible and practical 1H NMR analytical method for the quality control and quantification of bioactive principles in Lycii Fructus
10.1016/j.jfda.2018.01.001 2018-01-17 Lycii Fructus, a solanaceous drug, is widely used as functional foods and in Traditional Chinese Medicine. Samples collected from different regions of China have been found to be not identical in chemical compositions which might affect the biological activit... |