Caspofungin-d4

Modify Date: 2024-01-06 12:45:15

Caspofungin-d4 structure	Common Name	Caspofungin-d4
	CAS Number	1131958-73-0	Molecular Weight	1097.34
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₅₂H₈₄D₄N₁₀O₁₅	Melting Point	>101°C (dec.)
	MSDS	N/A	Flash Point	N/A

Use of Caspofungin-d4

Caspofungin-d4 (MK-0991-d4; L-743872-d4) is a deuterium labeled Caspofungin (HY-17006A). Caspofungin is a potent antifungal agent. Caspofungin inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan[1][2][3].

Name	Caspofungin Acetate-d4

Description	Caspofungin-d4 (MK-0991-d4; L-743872-d4) is a deuterium labeled Caspofungin (HY-17006A). Caspofungin is a potent antifungal agent. Caspofungin inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan[1][2][3].
Related Catalog	Research Areas >> Infection
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-246. [2]. Flattery AM, et, al. Efficacy of caspofungin in a juvenile mouse model of central nervous system candidiasis. Antimicrob Agents Chemother. 2011 Jul;55(7):3491-7. [3]. Mojumder DK, et, al. Evaluating retinal toxicity of intravitreal caspofungin in the mouse eye. Invest Ophthalmol Vis Sci. 2010 Nov;51(11):5796-803.

Description

Related Catalog

Research Areas >> Infection

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-246.

[2]. Flattery AM, et, al. Efficacy of caspofungin in a juvenile mouse model of central nervous system candidiasis. Antimicrob Agents Chemother. 2011 Jul;55(7):3491-7.

[3]. Mojumder DK, et, al. Evaluating retinal toxicity of intravitreal caspofungin in the mouse eye. Invest Ophthalmol Vis Sci. 2010 Nov;51(11):5796-803.

Melting Point	>101°C (dec.)
Molecular Formula	C₅₂H₈₄D₄N₁₀O₁₅
Molecular Weight	1097.34
Appearance of Characters	Solid \| White to Pale Beige
Storage condition	Hygroscopic, -20°C Freezer, Under inert atmosphere
Stability	Hygroscopic
Water Solubility	Methanol (Slightly, Sonicated), Water (Slightly, Heated)

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Caspofungin-d4

Use of Caspofungin-d4

Names

Caspofungin-d4 Biological Activity

Chemical & Physical Properties