PI3Kγ inhibitor 2

Modify Date: 2024-01-09 20:02:42

PI3Kγ inhibitor 2 structure	Common Name	PI3Kγ inhibitor 2
	CAS Number	1315538-79-4	Molecular Weight	433.38
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₁₈F₃N₅O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PI3Kγ inhibitor 2

PI3Kγ inhibitor 2 (Compound 16) is an orally bioavailable, CNS-penetrant, isoform selective PI3Kγ inhibitor with a Ki of 4 nM[1].

Name	PI3Kγ inhibitor 2

Description	PI3Kγ inhibitor 2 (Compound 16) is an orally bioavailable, CNS-penetrant, isoform selective PI3Kγ inhibitor with a Ki of 4 nM[1].
Related Catalog	Signaling Pathways >> PI3K/Akt/mTOR >> PI3K Research Areas >> Inflammation/Immunology
Target	PI3Kγ:4 nM (Ki)
References	[1]. Come JH, et al. Design and Synthesis of a Novel Series of Orally Bioavailable, CNS-Penetrant, Isoform Selective Phosphoinositide 3-Kinase γ (PI3Kγ) Inhibitors with Potential for the Treatment of Multiple Sclerosis (MS). J Med Chem. 2018 Jun 28;61(12):5245-5256.

Molecular Formula	C₂₀H₁₈F₃N₅O₃
Molecular Weight	433.38