Propargyl-peg3-sulfone-peg3-propargyl

Modify Date: 2024-01-16 16:09:38

Propargyl-peg3-sulfone-peg3-propargyl Structure
Propargyl-peg3-sulfone-peg3-propargyl structure
Common Name Propargyl-peg3-sulfone-peg3-propargyl
CAS Number 2055024-44-5 Molecular Weight 494.60
Density N/A Boiling Point N/A
Molecular Formula C22H38O10S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Propargyl-peg3-sulfone-peg3-propargyl


Propargyl-peg3-sulfone-peg3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Propargyl-peg3-sulfone-peg3-propargyl
Synonym More Synonyms

 Propargyl-peg3-sulfone-peg3-propargyl Biological Activity

Description Propargyl-peg3-sulfone-peg3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C22H38O10S
Molecular Weight 494.60

 Synonyms

MFCD30182062