HER2-IN-14

Modify Date: 2024-04-06 02:43:21

HER2-IN-14 Structure
HER2-IN-14 structure
Common Name HER2-IN-14
CAS Number 2414056-35-0 Molecular Weight 568.96
Density N/A Boiling Point N/A
Molecular Formula C26H23ClF2N8O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HER2-IN-14


HER2-IN-14 (Compound 34) is an HER2 inhibitor with an IC50 of 18 nM. HER2-IN-14 also inhibits wt-EGFR with an IC50 of 6.3 μM[1].

 Names

Name HER2-IN-14

 HER2-IN-14 Biological Activity

Description HER2-IN-14 (Compound 34) is an HER2 inhibitor with an IC50 of 18 nM. HER2-IN-14 also inhibits wt-EGFR with an IC50 of 6.3 μM[1].
Related Catalog
Target

HER2:18 nM (IC50)

EGFR (WT):6.3 μM (IC50)

References

[1]. Ding Zhou, et al. Quinazoline derivatives as antitumor agents. Patent WO2020057511A1.

 Chemical & Physical Properties

Molecular Formula C26H23ClF2N8O3
Molecular Weight 568.96
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