N,N-Dimethylglycine-d6 hydrochloride

Modify Date: 2024-01-23 20:27:37

N,N-Dimethylglycine-d6 hydrochloride Structure
N,N-Dimethylglycine-d6 hydrochloride structure
Common Name N,N-Dimethylglycine-d6 hydrochloride
CAS Number 347840-03-3 Molecular Weight 145.62
Density N/A Boiling Point 190-192ºC(lit.)
Molecular Formula C4H4D6ClNO2 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of N,N-Dimethylglycine-d6 hydrochloride


N,N-Dimethylglycine-d6 hydrochloride is the deuterium labeled N,N-Dimethylglycine[1].

 Names

Name 2-[bis(trideuteriomethyl)amino]acetic acid,hydrochloride
Synonym More Synonyms

 N,N-Dimethylglycine-d6 hydrochloride Biological Activity

Description N,N-Dimethylglycine-d6 hydrochloride is the deuterium labeled N,N-Dimethylglycine[1].
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Boiling Point 190-192ºC(lit.)
Molecular Formula C4H4D6ClNO2
Molecular Weight 145.62
Exact Mass 145.07800
PSA 40.54000
LogP 0.43460

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases 36/38
Safety Phrases 26-36/37
RIDADR NONH for all modes of transport

 Synonyms

N,N-Dimethyl-d6-glycine hydrochloride
N-Methylsarcosine-dimethyl-d6 hydrochloride