Pyruvic acid-13C-2 sodium

Modify Date: 2024-01-13 20:02:31

Pyruvic acid-13C-2 sodium Structure
Pyruvic acid-13C-2 sodium structure
Common Name Pyruvic acid-13C-2 sodium
CAS Number 87976-71-4 Molecular Weight 111.03700
Density N/A Boiling Point N/A
Molecular Formula C3H3NaO3 Melting Point >300ºC(lit.)
MSDS Chinese USA Flash Point N/A

 Use of Pyruvic acid-13C-2 sodium


Pyruvic acid-13C-2 (sodium) is the 13C labeled Pyruvic acid[1]. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats[2].

 Names

Name sodium,2-oxopropanoate
Synonym More Synonyms

 Pyruvic acid-13C-2 sodium Biological Activity

Description Pyruvic acid-13C-2 (sodium) is the 13C labeled Pyruvic acid[1]. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Kładna A, et al. Reactivity of pyruvic acid and its derivatives towards reactive oxygen species. Luminescence. 2015 Nov;30(7):1153-8.  

 Chemical & Physical Properties

Melting Point >300ºC(lit.)
Molecular Formula C3H3NaO3
Molecular Weight 111.03700
Exact Mass 111.00100
PSA 57.20000

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3

 Synthetic Route

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Pyruvic acid-13C-2 sodium Structure

Pyruvic acid-13...

CAS#:87976-71-4

Literature: US2006/178534 A1, ; Page/Page column 4-5 ;

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Pyruvic acid-13C-2 sodium Structure

Pyruvic acid-13...

CAS#:87976-71-4

Literature: WO2006/11809 A1, ; Page/Page column 21 ;

 Synonyms

PYRUVIC-1-13C ACID SODIUM SALT
(13)C1-sodium pyruvate
Pyruvic acid-1-13C sodium salt
PYRUVIC ACID, SODIUM SALT (1-13C)
Sodium pyruvate-1-13C
sodium [1-(13)C]pyruvate
MFCD00084079
2-oxo-[1-13C]propanoic acid sodium salt
sodium (13)C-1-pyruvate
Propanoic-1-13Cacid,2-oxo-,sodium salt (9CI)
(1-13C)-sodium pyruvate
(1-13C)-pyruvate sodium salt
Sodium Pyruvate (1-13C, 99%)