Dimethyl succinate
Names
[ CAS No. ]:
106-65-0
[ Name ]:
Dimethyl succinate
[Synonym ]:
Butanedioic acid dimethyl ester
EINECS 203-419-9
dimethyl butanedioate
Succinic Acid Dimethyl Ester
Methyl succinate
MFCD00008466
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
195.3±0.0 °C at 760 mmHg
[ Melting Point ]:
16-19 °C(lit.)
[ Molecular Formula ]:
C6H10O4
[ Molecular Weight ]:
146.141
[ Flash Point ]:
85.0±0.0 °C
[ Exact Mass ]:
146.057907
[ PSA ]:
52.60000
[ LogP ]:
0.20
[ Vapour Pressure ]:
0.4±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.411
[ Stability ]:
Stable. Combustible. Incompatible with oxidizing agents, acids, bases, reducing agents.
[ Water Solubility ]:
8.5 g/L (20 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WM7675000
- CHEMICAL NAME :
- Succinic acid, dimethyl ester
- CAS REGISTRY NUMBER :
- 106-65-0
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C6-H10-O4
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 18,677,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 18,677,1980 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6235 No. of Facilities: 1260 (estimated) No. of Industries: 8 No. of Occupations: 18 No. of Employees: 15417 (estimated) No. of Female Employees: 6678 (estimated)
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R36
[ Safety Phrases ]:
S26-S24/25
[ RIDADR ]:
UN 1993
[ WGK Germany ]:
1
[ RTECS ]:
WM7675000
[ HS Code ]:
29171990
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2917190090
[ Summary ]:
2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
PLoS ONE 9(12) , e115144, (2014)
Recent work has highlighted glutaminase (GLS) as a key player in cancer cell metabolism, providing glutamine-derived carbon and nitrogen to pathways that support proliferation. There is significant in...
Process model and economic analysis of itaconic acid production from dimethyl succinate and formaldehyde.Bioresour. Technol. 97(2) , 342-7, (2006)
A complete process model and economic analysis has been developed for itaconic acid production via catalytic condensation of dimethyl succinate and formaldehyde. The process model is based on experime...
Effects of the methyl esters of pyruvate, succinate and glutamate on the secretory response to meglitinide analogues in rat pancreatic islets.Pharmacol. Res. 33(3) , 191-4, (1996)
The insulinotropic action of the meglitinide analogues KAD-1229, A-4166 and repaglinide was examined in rat pancreatic islets deprived of exogenous nutrient or incubated in the presence of nutrient se...