Glutaric Anhydride
Names
[ CAS No. ]:
108-55-4
[ Name ]:
Glutaric Anhydride
[Synonym ]:
2H-Pyran-2,6(3H)-dione, dihydro
2H-Pyran-2,6(3H)-dione, dihydro-
dihydro-3H-pyran-2,6-dione
Glutaric anhydride
Glutaric acid anhydride
Dihydro-2H-pyran-2,6(3H)-dione
Dihydro-pyran-2,6-dione
EINECS 203-593-6
MFCD00006679
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
287.0±0.0 °C at 760 mmHg
[ Melting Point ]:
50-55 °C(lit.)
[ Molecular Formula ]:
C5H6O3
[ Molecular Weight ]:
114.099
[ Flash Point ]:
120.9±15.9 °C
[ Exact Mass ]:
114.031693
[ PSA ]:
43.37000
[ LogP ]:
-0.92
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.463
[ Storage condition ]:
2-8°C
[ Water Solubility ]:
hydrolysis
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MA3850000
- CHEMICAL NAME :
- Glutaric anhydride
- CAS REGISTRY NUMBER :
- 108-55-4
- BEILSTEIN REFERENCE NO. :
- 0110051
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C5-H6-O3
- MOLECULAR WEIGHT :
- 114.11
- WISWESSER LINE NOTATION :
- T6VOVTJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 540 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Gastrointestinal - necrotic changes Liver - hepatitis (hepatocellular necrosis), diffuse
- REFERENCE :
- TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 36(1,pt2),272,1997
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1780 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962
Safety Information
[ Symbol ]:
GHS05, GHS07
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302-H312-H315-H318-H335
[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R21/22;R36/37/38
[ Safety Phrases ]:
S26-S36/39-S36/37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
MA3850000
[ HS Code ]:
2917190090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2917190090
[ Summary ]:
2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Clin. Chem. Lab Med. 53(5) , 801-8, (2015)
The parallelization of clinically relevant antigens in a microarray format is of growing importance due to the ability to measure multiple antigen-antibody interactions. With the development of a micr...
Metal-organic framework UiO-66 modified magnetite@silica core-shell magnetic microspheres for magnetic solid-phase extraction of domoic acid from shellfish samples.J. Chromatogr. A. 1400 , 10-8, (2015)
Fe3O4@SiO2@UiO-66 core-shell magnetic microspheres were synthesized and characterized by transmission electron microscopy, scanning electron microscopy, X-ray diffraction, Fourier transform infrared s...
Synthesis and evaluation of chloramphenicol homodimers: molecular target, antimicrobial activity, and toxicity against human cells.PLoS ONE 10 , e0134526, (2015)
As fight against antibiotic resistance must be strengthened, improving old drugs that have fallen in reduced clinical use because of toxic side effects and/or frequently reported resistance, like chlo...