2-Methylaminoethanol
Names
[ CAS No. ]:
109-83-1
[ Name ]:
2-Methylaminoethanol
[Synonym ]:
MFCD00002839
2-Hydroxypropanamine
2-(Methylamino)ethanol
(RS)-1-Amino-2-hydroxypropane
1-Amino-2-hydroxypropane
propan-2-ol, 1-amino-
N-Methylethanolamine
2-Methylaminoethanol
(±)-1-Amino-2-propanol
1-Aminopropan-2-ol
(RS)-1-amino-2-propanol
2-Propanol, 1-amino- (8CI,9CI)
UNII:UE40BY1BZW
2-Hydroxy-1-propylamine
2-Propanol, 1-amino-
EINECS 203-710-0
(±)-Isopropanolamine
1-Amino-2-propanol
2-Propanol, 1-amino-, (±)-
Chemical & Physical Properties
[ Density]:
0.9±0.1 g/cm3
[ Boiling Point ]:
159.9±13.0 °C at 760 mmHg
[ Melting Point ]:
-3 °C
[ Molecular Formula ]:
C3H9NO
[ Molecular Weight ]:
75.110
[ Flash Point ]:
73.9±0.0 °C
[ Exact Mass ]:
75.068413
[ PSA ]:
32.26000
[ LogP ]:
-0.96
[ Vapour density ]:
2.6 (vs air)
[ Vapour Pressure ]:
0.9±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.440
[ Stability ]:
Stable. Combustible. Incompatible with oxidizing agents.
[ Water Solubility ]:
miscible
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KL6650000
- CHEMICAL NAME :
- Ethanol, 2-(methylamino)-
- CAS REGISTRY NUMBER :
- 109-83-1
- BEILSTEIN REFERENCE NO. :
- 1071196
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 10
- MOLECULAR FORMULA :
- C3-H9-N-O
- MOLECULAR WEIGHT :
- 75.13
- WISWESSER LINE NOTATION :
- Q2M1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Open irritation test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 1/20/1972 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2340 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 10,61,1954
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1330 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 12,486,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 125 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1802 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - coma Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 225,428,1955
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1070 uL/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - other changes Skin and Appendages - dermatitis, other (after systemic exposure)
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0536158 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4016 No. of Facilities: 7733 (estimated) No. of Industries: 36 No. of Occupations: 28 No. of Employees: 39013 (estimated) No. of Female Employees: 11887 (estimated)
Safety Information
[ Symbol ]:
GHS05, GHS07, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302 + H312-H314-H335-H373
[ Precautionary Statements ]:
P280-P301 + P312 + P330-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338
[ Target Organs ]:
Epididymus, Kidney, Liver, Testes, ovary, spleen
[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
C:Corrosive;
[ Risk Phrases ]:
R21/22;R34
[ Safety Phrases ]:
S26-S36/37/39-S45
[ RIDADR ]:
UN 2735 8/PG 2
[ WGK Germany ]:
1
[ RTECS ]:
KL6650000
[ Packaging Group ]:
III
[ Hazard Class ]:
8
[ HS Code ]:
29221980
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922199090
[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
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