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Dodecanoyl chloride

Names

[ CAS No. ]:
112-16-3

[ Name ]:
Dodecanoyl chloride

[Synonym ]:
LAURIC ACID CHLORIDE
LAUROYL CHLORIDE FOR SYNTHESIS
Lauric chloride
EINECS 203-941-7
Lauroyl Chloride
MFCD00000740
dodecanoic acid chloride
n-Dodecanoyl chloride
LACL
Dodecanoyl chloride
lauroyl chloroformate

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
266.6±3.0 °C at 760 mmHg

[ Melting Point ]:
-17 °C

[ Molecular Formula ]:
C12H23ClO

[ Molecular Weight ]:
218.763

[ Flash Point ]:
122.0±7.4 °C

[ Exact Mass ]:
218.143738

[ PSA ]:
17.07000

[ LogP ]:
5.77

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.445

[ Storage condition ]:
−20°C

[ Stability ]:
Stable. Incompatible with strong oxidizing agents, amines, strong bases. Do not allow to come into contact with water or moisture.

[ Water Solubility ]:
reacts

MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R14;R22;R29;R34

[ Safety Phrases ]:
S26-S36/37/39-S45-S8

[ RIDADR ]:
UN 3265 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
29159080

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2915900090

[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

Articles

Lipophilic prodrugs of apomorphine I: preparation, characterisation, and in vitro enzymatic hydrolysis in biorelevant media.

Eur. J. Pharm. Biopharm. 89 , 216-23, (2015)

Apomorphine, a subcutaneously administered drug for Parkinson's disease with short half-life requires frequent administration leading to patient non-compliance. This study aimed at synthesising and pu...

Use of multivariate statistical techniques to optimize the separation of 17 capsinoids by ultra performance liquid chromatography using different columns.

Talanta 134 , 256-63, (2015)

In this work a multivariate statistical tool (Derringer and Suich optimization) was proposed for the separation of seventeen capsinoids (natural and synthetic) using the UHPLC-DAD chromatography. Caps...

Tartaric acid-based amphiphilic macromolecules with ether linkages exhibit enhanced repression of oxidized low density lipoprotein uptake.

Biomaterials 53 , 32-9, (2015)

Cardiovascular disease initiates with the atherogenic cascade of scavenger receptor- (SR-) mediated oxidized low-density lipoprotein (oxLDL) uptake. Resulting foam cell formation leads to lipid-rich l...


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