2,4,6-Tribromophenol
Names
[ CAS No. ]:
118-79-6
[ Name ]:
2,4,6-Tribromophenol
[Synonym ]:
BROMOL
2,3-DIHYDRO-INDOLE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 3-METHYL ESTER
EINECS 204-278-6
2,4,6-Tribromophenol
TA 10
HOC6H2Br3-2.4.6
2,4,6-tribromo-phenol
Tribromophenol
MFCD00002150
Flammex 3BP
Bromkal pur 3
2,4,6-Tribromo-1-hydroxybenzene
2,4,6-tribrom-1-phenol
Phenol,2,4,6-tribromo
Phenol, 2,4,6-tribromo-
2,4,6-tribormophenol
Xeroform
Chemical & Physical Properties
[ Density]:
2.4±0.1 g/cm3
[ Boiling Point ]:
286.8±0.0 °C at 760 mmHg
[ Melting Point ]:
90-94 °C(lit.)
[ Molecular Formula ]:
C6H3Br3O
[ Molecular Weight ]:
330.799
[ Flash Point ]:
109.7±25.9 °C
[ Exact Mass ]:
327.773376
[ PSA ]:
20.23000
[ LogP ]:
4.33
[ Vapour density ]:
11.4 (vs air)
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.674
[ Storage condition ]:
2-8°C
[ Water Solubility ]:
71 mg/L (15 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SN1225000
- CHEMICAL NAME :
- Phenol, 2,4,6-tribromo-
- CAS REGISTRY NUMBER :
- 118-79-6
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C6-H3-Br3-O
- MOLECULAR WEIGHT :
- 330.82
- WISWESSER LINE NOTATION :
- QR BE DE FE
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0523296 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,524,1986
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >1630 mg/m3/4H
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Sense Organs and Special Senses (Eye) - ptosis
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0523305
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 3 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0522208 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 920 mg/m3/6H/3W-I
- TOXIC EFFECTS :
- Gastrointestinal - changes in structure or function of salivary glands Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Related to Chronic Data - death
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0536719
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 100 mg/m3/6H/3W-I
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Gastrointestinal - changes in structure or function of salivary glands Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0523305 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4026 No. of Facilities: 64 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 1427 (estimated) No. of Female Employees: 734 (estimated)
Safety Information
[ Symbol ]:
GHS07, GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H317-H319-H400
[ Precautionary Statements ]:
P273-P280-P305 + P351 + P338
[ Hazard Codes ]:
Xn:Harmful
[ Risk Phrases ]:
R20/22;R36/37/38;R51/53
[ Safety Phrases ]:
S26-S36-S61-S37/39-S45-S36/37-S16-S7-S24/25-S23-S53
[ RIDADR ]:
UN 1230 3/PG 2
[ WGK Germany ]:
2
[ RTECS ]:
SN1225000
[ Packaging Group ]:
I; II; III
[ HS Code ]:
2908199090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2908199090
[ Summary ]:
HS: 2908199090. derivatives of polyphenols or phenol-alcohols containing only halogen substituents and their salts. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tariff:5.5%. general tariff:30.0%
Articles
Ecotoxicol. Environ. Saf. 104 , 220-5, (2014)
The effect of concurrent degradation of tetrabromobisphenol A (TBBPA) by the strain Ochrobactrum sp. T under aerobic condition was investigated. The results demonstrated that four extra energy source-...
Self-Assembly of a Tripod Aromatic Rod into Stacked Planar Networks.Chemistry 21 , 11836-42, (2015)
Threefold symmetric rigid-core molecules with an internally grafted poly(ethylene oxide) (PEO) chain were synthesized, and their self-assembled structures were characterized using differential scannin...
Structural and kinetic study of an internal substrate binding site in dehaloperoxidase-hemoglobin A from Amphitrite ornata.Biochemistry 52(14) , 2427-39, (2013)
X-ray crystal structures of dehaloperoxidase-hemoglobin A (DHP A) from Amphitrite ornata soaked with substrate, 2,4,6-tribromophenol (2,4,6-TBP), in buffer solvent with added methanol (MeOH), 2-propan...