2,2'-Dithiobis(benzothiazole)
Names
[ CAS No. ]:
120-78-5
[ Name ]:
2,2'-Dithiobis(benzothiazole)
[Synonym ]:
2,2'-Dithiobis(benzothiazole)
2,2'-Disulfanediylbis(1,3-benzothiazol)
Mercaptobenztiazyl Ether
Perkacit MBTS
2,2'-Disulfanediylbis(1,3-benzothiazole)
Benzothiazol-2-yl disulfide
2,2-Dithiobisbenzothiazole
EINECS 204-424-9
2,2'-Dibenzothiazyl disulfide
2,2'-Dithiobis[benzothiazole]
2-(1,3-benzothiazol-2-yldisulfanyl)-1,3-benzothiazole
2,2'-Dibenzothiazolyl Disulfide
1,2-Bis(benzo[d]thiazol-2-yl)disulfane
2,2'-Dithiobisbenzothiazole
Benzothiazole, 2,2'-dithiobis-
MFCD00022874
2,2′-Dithiobis(benzothiazole)
MBTS
Chemical & Physical Properties
[ Density]:
1.6±0.1 g/cm3
[ Boiling Point ]:
532.5±33.0 °C at 760 mmHg
[ Melting Point ]:
177-180 °C(lit.)
[ Molecular Formula ]:
C14H8N2S4
[ Molecular Weight ]:
332.487
[ Flash Point ]:
275.8±25.4 °C
[ Exact Mass ]:
331.957031
[ PSA ]:
132.86000
[ LogP ]:
7.04
[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C
[ Index of Refraction ]:
1.849
[ Water Solubility ]:
<0.01 g/100 mL at 21 ºC
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DL4550000
- CHEMICAL NAME :
- Benzothiazole, 2,2'-dithiobis-
- CAS REGISTRY NUMBER :
- 120-78-5
- BEILSTEIN REFERENCE NO. :
- 0285796
- LAST UPDATED :
- 199804
- DATA ITEMS CITED :
- 18
- MOLECULAR FORMULA :
- C14-H8-N2-S4
- MOLECULAR WEIGHT :
- 332.48
- WISWESSER LINE NOTATION :
- T56 BN DSJ CSS- CT56 BN DSJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >12 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 7 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 180 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >7940 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 9100 mg/kg/13W-I
- TOXIC EFFECTS :
- Liver - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 172 gm/kg/78W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Blood - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Parenteral
- DOSE :
- 400 mg/kg
- SEX/DURATION :
- female 4-11 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Parenteral
- DOSE :
- 400 mg/kg
- SEX/DURATION :
- female 4-11 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetal death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Parenteral
- DOSE :
- 800 mg/kg
- SEX/DURATION :
- male 2 day(s) pre-mating female 2 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Parenteral
- DOSE :
- 800 mg/kg
- SEX/DURATION :
- male 2 day(s) pre-mating female 2 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetal death
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Rodent - mouse Lymphocyte
- DOSE/DURATION :
- 15 mg/L
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 5,193,1983 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84830 No. of Facilities: 897 (estimated) No. of Industries: 12 No. of Occupations: 28 No. of Employees: 11180 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84830 No. of Facilities: 1533 (estimated) No. of Industries: 19 No. of Occupations: 42 No. of Employees: 50590 (estimated) No. of Female Employees: 11091 (estimated)
Safety Information
[ Symbol ]:
GHS07, GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H317-H410
[ Supplemental HS ]:
Contact with acids liberates toxic gas.
[ Precautionary Statements ]:
P273-P280-P501
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xi:Irritant
[ Risk Phrases ]:
R31;R43;R50/53
[ Safety Phrases ]:
S36/37-S60-S61
[ RIDADR ]:
UN 3077 9/PG 3
[ WGK Germany ]:
2
[ RTECS ]:
DL4550000
[ Hazard Class ]:
9.0
[ HS Code ]:
2934200090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2934999090
[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Chem. Commun. (Camb.) (6) , 592-4, (2007)
The solid state interaction of mono and macromolecular thiols at a disulfide heterocycle is shown to provide a versatile pathway for their speciation.
A wood preservative metabolite in river water.Environ. Sci. Pollut. Res. Int. 12(1) , 8-9, (2005)
A previously unknown pollutant in river water was identified to be 2-mercaptobenzothiazole (2-MBT) by interpretation and simulation of its GC/LRMS spectrum. Further GC/HRMS measurement of the isotope ...
Allergic contact dermatitis from mercapto compounds.Dermatitis 17(2) , 56-70, (2006)
Despite being well-known allergens, mercaptobenzothiazole and its derivatives continue to be widely used in natural and synthetic rubber, in the mining industry, and in a variety of nonrubber products...