NSC 204421

Names

[ CAS No. ]:
132-66-1

[ Name ]:
NSC 204421

[Synonym ]:
alanap
2-(naphthalen-1-ylcarbamoyl)benzoic acid
2-(1-Naphthylcarbamoyl)benzoic acid
NAPTRO
acp322
dyanap
solo
alanape
N-(1-Naphthyl)phthalamic Acid
MFCD00037725
N-1-naphthylphthalamic acid
cyanap
2-[(1-naphthalenylamino)carbonyl]benzoic acid
alanap1
2-[(1-naphthylamino)carbonyl]benzoic acid
N-(1-Naphthyl)phthalamidic acid
NAPTALAM
6q8
2-<(1-naphthalenylamino)carbonyl>benzoic acid
NPA

Biological Activity

[Description]:

N-1-Naphthylphthalamic acid is a polar auxin transport inhibitor. N-1-Naphthylphthalamic acid disrupts leaf initiation, KNOX protein regulation, and formation of leaf margins in maize[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Ihsan BurakCam, et al. Physical and chemical properties of cow cockle seeds (Vaccaria hispanica (Mill.) Rauschert) genetic resources of Turkey.

Chemical & Physical Properties

[ Density]:
1.355g/cm3

[ Boiling Point ]:
450.8ºC at 760mmHg

[ Melting Point ]:
185-190 °C

[ Molecular Formula ]:
C₁₈H₁₃NO₃

[ Molecular Weight ]:
291.30

[ Flash Point ]:
226.4ºC

[ Exact Mass ]:
291.09000

[ PSA ]:
66.40000

[ LogP ]:
3.86330

[ Vapour Pressure ]:
6.51E-09mmHg at 25°C

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TH7350000

CHEMICAL NAME :: Phthalamic acid, N-1-naphthyl-

CAS REGISTRY NUMBER :: 132-66-1

BEILSTEIN REFERENCE NO. :: 2814102

LAST UPDATED :: 199706

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C18-H13-N-O3

MOLECULAR WEIGHT :: 291.32

WISWESSER LINE NOTATION :: L66J BMVR BVQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C215,1991

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2070 mg/m3

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,613,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,613,1991 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

Safety Information

[ Hazard Statements ]:
H412

[ Precautionary Statements ]:
P273

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R36/37/38:Irritating to eyes, respiratory system and skin .

[ Safety Phrases ]:
S26-S36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
TH7350000

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Non-invasive quantification of endogenous root auxin transport using an integrated flux microsensor technique.

Plant J. 63(6) , 1004-16, (2010)

Indole-3-acetic acid (IAA) is a primary phytohormone that regulates multiple aspects of plant development. Because polar transport of IAA is an essential determinant of organogenesis and dynamic tropi...

Auxin modulates the enhanced development of root hairs in Arabidopsis thaliana (L.) Heynh. under elevated CO(2).

Plant Cell Environ. 34(8) , 1304-17, (2011)

Root hairs may play a critical role in nutrient acquisition of plants grown under elevated CO(2) . This study investigated how elevated CO(2) enhanced the development of root hairs in Arabidopsis thal...

Expression profile of PIN, AUX/LAX and PGP auxin transporter gene families in Sorghum bicolor under phytohormone and abiotic stress.

FEBS J. 277 , 2954-2969, (2010)

Auxin is transported by the influx carriers auxin resistant 1/like aux1 (AUX/LAX), and the efflux carriers pin-formed (PIN) and P-glycoprotein (PGP), which play a major role in polar auxin transport. ...

Related Compounds

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