Naphthoresorcinol
Names
[ CAS No. ]:
132-86-5
[ Name ]:
Naphthoresorcinol
[Synonym ]:
EINECS 205-079-7
Naphthalene-1,3-diol
1,3-Naphthalenediol
MFCD00003965
Naphthoresorcinol
1,3-dihydroxynaphthalene
Benzoresorcinol
1,3-Naphthalenediol,Naphthoresorcinol
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
361.5±9.0 °C at 760 mmHg
[ Melting Point ]:
123-125 °C(lit.)
[ Molecular Formula ]:
C10H8O2
[ Molecular Weight ]:
160.169
[ Flash Point ]:
185.5±13.3 °C
[ Exact Mass ]:
160.052429
[ PSA ]:
40.46000
[ LogP ]:
1.99
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.726
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QJ4725000
- CHEMICAL NAME :
- 1,3-Naphthalenediol
- CAS REGISTRY NUMBER :
- 132-86-5
- BEILSTEIN REFERENCE NO. :
- 2044002
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C10-H8-O2
- MOLECULAR WEIGHT :
- 160.18
- WISWESSER LINE NOTATION :
- L66J BQ DQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 625 nmol/plate
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 371,293,1996 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6606 No. of Facilities: 73 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 2798 (estimated) No. of Female Employees: 1388 (estimated)
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
QJ4725000
[ HS Code ]:
2907299090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2907299090
[ Summary ]:
2907299090 polyphenols; phenol-alcohols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%
Articles
J. Med. Chem. 49 , 1932-8, (2006)
The antiproliferative activity of the 14 isomeric monoxylosylated dihydroxynaphthalenes has been tested in vitro toward normal HFL-1 and 3T3 A31 cells as well as transformed T24 and 3T3 SV40 cells. Th...
Mutagenicity of products formed by ozonation of naphthoresorcinol in aqueous solutions.Mutat. Res. 189(3) , 217-22, (1987)
The mutagenicity of products formed by ozonation of naphthoresorcinol in aqueous solution was assayed with Salmonella typhimurium strains TA97, TA98, TA100, TA102 and TA104 in the presence and absence...
Effector-repressor interactions, binding of a single effector molecule to the operator-bound TtgR homodimer mediates derepression.J. Biol. Chem. 281(11) , 7102-9, (2006)
The RND family transporter TtgABC and its cognate repressor TtgR from Pseudomonas putida DOT-T1E were both shown to possess multidrug recognition properties. Structurally unrelated molecules such as c...