Ethylenediaminetetraacetic acid disodium salt
Names
[ CAS No. ]:
139-33-3
[ Name ]:
Ethylenediaminetetraacetic acid disodium salt
[Synonym ]:
EDTA disodium salt
4C EDTA
Titriplex III
Tetracemate disodium
ethylenediaminetetraacetic acid disodium
DISODIUM EDTA
Ethylenediaminetetraacetic acid disodium s
(Ethylenedinitrilo)tetraacetic acid disodium salt,EDTA disodium salt,EDTA-Na2
Disotate
aqueous Na2EDTA
kiresutob
Ethylenediaminetetraacetic acid, disodium salt
EDTA NA2
chelaplex
Endrate disodium
EINECS 205-358-3
Disodium salt of EDTA
(Ethylenedinitrilo)tetraacetic acid disodium salt
Ethylenediaminetetraacetic acid,disodium salt,DNAse
Edetic acid disodium salt
trilonbd
MFCD00070672
cheladrate
Disodium 2,2'-{1,2-ethanediylbis[(carboxymethyl)imino]}diacetate
Ethylenediaminetetraaceticaciddisodiumsalt
ethylenediaminetetraaceticacetate sodium
Chelaplex III
Edetate disodium
Sodium N,N'-ethane-1,2-diylbis(N-(carboxymethyl)glycinate)
Acetic acid, (ethylenedinitrilo)tetra-, disodium salt
disodium 2,2'-{ethane-1,2-diylbis[(carboxymethyl)imino]}diacetate
Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, disodium salt
EDTA disodium
disodium ethylenediaminetetraacetate
Triplex III
dotite2na
Versene Disodium Salt
EDTA-2NA
Ethylenediaminetetraacetic Acid Disodium Salt
EDTA Disodium Dihydrate
Chemical & Physical Properties
[ Density]:
1.01 g/mL at 25 °C
[ Boiling Point ]:
>100 °C
[ Melting Point ]:
248 °C (dec.)(lit.)
[ Molecular Formula ]:
C10H14N2Na2O8
[ Molecular Weight ]:
336.206
[ Flash Point ]:
325.2ºC
[ Exact Mass ]:
336.054565
[ PSA ]:
161.34000
[ Vapour Pressure ]:
1.15E-16mmHg at 25°C
[ Storage condition ]:
2-8°C
[ Water Solubility ]:
H2O: clear, colorless
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AH4375000
- CHEMICAL NAME :
- Acetic acid, (ethylenedinitrilo)tetra-, disodium salt
- CAS REGISTRY NUMBER :
- 139-33-3
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 21
- MOLECULAR FORMULA :
- C10-H14-N2-O8.2Na
- MOLECULAR WEIGHT :
- 336.24
- WISWESSER LINE NOTATION :
- QV1N1VQ2N1VQ1VQ &-NA- 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2050 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 260 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 56 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 2300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 47 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 540 gm/kg/90D-I
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 15 gm/kg/30D-I
- TOXIC EFFECTS :
- Liver - other changes Kidney, Ureter, Bladder - other changes Endocrine - other changes
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 300 mg/kg/30D-I
- TOXIC EFFECTS :
- Liver - other changes Kidney, Ureter, Bladder - other changes Endocrine - other changes
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 31429 mg/kg
- SEX/DURATION :
- female 1-22 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 12857 mg/kg
- SEX/DURATION :
- female 7-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Embryo or Fetus - fetal death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 12857 mg/kg
- SEX/DURATION :
- female 7-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - eye/ear Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 12857 mg/kg
- SEX/DURATION :
- female 7-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 380 mg/kg
- SEX/DURATION :
- female 9 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
- TYPE OF TEST :
- Cytogenetic analysis
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 15 mg/kg
- REFERENCE :
- FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 29,845,1991 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83643 No. of Facilities: 5010 (estimated) No. of Industries: 45 No. of Occupations: 47 No. of Employees: 43360 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83643 No. of Facilities: 8199 (estimated) No. of Industries: 62 No. of Occupations: 69 No. of Employees: 106998 (estimated) No. of Female Employees: 62467 (estimated)
Safety Information
[ Symbol ]:
GHS05
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H314
[ Precautionary Statements ]:
P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Gloves
[ Hazard Codes ]:
Xn:Harmful
[ Risk Phrases ]:
R22;R36/37/38
[ Safety Phrases ]:
S26-S36-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
2
[ RTECS ]:
AH4410000
[ HS Code ]:
2922499990
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922499990
[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%
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