Hexetidine
Names
[ CAS No. ]:
141-94-6
[ Name ]:
Hexetidine
[Synonym ]:
1,3-Bis(b-ethylhexyl)-5-methyl-5-aminohexahydropyrimidine
5-Amino-1,3-di(b-ethylhexyl)hexahydro-5-methylpyrimidine
Hexetidine
Hexopyrimidine
UNII:852A84Y8LS
EINECS 205-513-5
5-Pyrimidinamine, 1,3-bis(2-ethylhexyl)hexahydro-5-methyl-
MFCD00010428
1,3-Bis(2-ethylhexyl)-5-methylhexahydro-5-pyrimidinamine
1,3-Bis(2-ethylhexyl)-5-methylhexahydropyrimidin-5-amine
1,3-bis(2-ethylhexyl)-5-methyl-1,3-diazinan-5-amine
1,3-Bis(2-ethylhexyl)hexahydro-5-methyl-5-pyrimidinamine
steri/sol
Biological Activity
[Description]:
[Related Catalog]:
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
0.9±0.1 g/cm3
[ Boiling Point ]:
388.2±0.0 °C at 760 mmHg
[ Molecular Formula ]:
C21H45N3
[ Molecular Weight ]:
339.602
[ Flash Point ]:
175.0±13.8 °C
[ Exact Mass ]:
339.361359
[ PSA ]:
32.50000
[ LogP ]:
7.15
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.467
[ Storage condition ]:
2-8℃
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ HS Code ]:
2933599090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933599090
[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Pharm. Res. 19(6) , 818-24, (2002)
Ventilator-associated pneumonia is a frequent cause of mortality in intensive care patients. This study describes the physicochemical properties of hexetidine-impregnated poly(vinyl chloride) (PVC) en...
The effect of hexetidine mouthwash on the prevention of plaque and gingival inflammation: a systematic review.Int. J. Dent. Hyg. 9(3) , 182-90, (2011)
To review the literature concerning hexetidine-containing mouthwash as a monotherapy or as an adjunct to oral hygiene in the prevention of plaque accumulation and gingival inflammation.PubMed-MEDLINE ...
The plaque inhibitory effect of a CPC mouthrinse in a 3-day plaque accumulation model - a cross-over study.Int. J. Dent. Hyg. 8(4) , 269-75, (2010)
To test the plaque inhibitory effect of an experimental 0.07% cetylpyridinium chloride (CPC) mouthrinse in a 3-day plaque accumulation model in a cross-over design.A total of 30 subjects (non-dental s...