2-BROMOACRYLALDEHYDE
Names
[ CAS No. ]:
14925-39-4
[ Name ]:
2-BROMOACRYLALDEHYDE
[Synonym ]:
2-Bromo-2-propenal
2-Bromoacrylaldehyde
2-Bromo-acrylaldehyde,2-Bromopropenal
bromoacrolein
2-bromoprop-2-enal
2-Bromopropenal
Chemical & Physical Properties
[ Density]:
1.617g/cm3
[ Boiling Point ]:
149.1ºC at 760mmHg
[ Molecular Formula ]:
C3H3BrO
[ Molecular Weight ]:
134.95900
[ Flash Point ]:
97.2ºC
[ Exact Mass ]:
133.93700
[ PSA ]:
17.07000
[ LogP ]:
1.09390
[ Vapour Pressure ]:
4.08mmHg at 25°C
[ Index of Refraction ]:
1.473
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AS1110000
- CHEMICAL NAME :
- Acrolein, 2-bromo-
- CAS REGISTRY NUMBER :
- 14925-39-4
- BEILSTEIN REFERENCE NO. :
- 1698247
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C3-H3-Br-O
- MOLECULAR WEIGHT :
- 134.97
- WISWESSER LINE NOTATION :
- VHYEU1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1200 mg/kg/2W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors
MUTATION DATA
- TYPE OF TEST :
- Morphological transformation
- TEST SYSTEM :
- Rodent - hamster Embryo
- DOSE/DURATION :
- 500 nmol/L
- REFERENCE :
- CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 6,705,1985
Safety Information
[ Symbol ]:
GHS05, GHS06, GHS09
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H300-H311 + H331-H314-H400
[ Precautionary Statements ]:
P280-P301 + P310 + P330-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338-P403 + P233
[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
T,N
[ Risk Phrases ]:
23/24/25-34-50
[ Safety Phrases ]:
26-36/37/39-45-61
[ RIDADR ]:
UN3286 3/PG 2
[ RTECS ]:
AS1110000
[ HS Code ]:
2913000090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2913000090
[ Summary ]:
HS: 2913000090 halogenated, sulphonated, nitrated or nitrosated derivatives of products of heading 2912 Educational tariff:17.0% Tax rebate rate:9.0% Regulatory conditions:none Most favored nation tariff:5.5% General tariff:30.0%
Articles
Hum. Exp. Toxicol. 13(12) , 861-5, (1994)
1. The genotoxicity of the flame retardant tris(2,3-dibromopropyl)phosphate (Tris-BP) was studied in vivo. Results showed that Tris-BP was highly clastogenic, but it could only initiate a low number o...
Genotoxicity of 2-halosubstituted enals and 2-chloroacrylonitrile in the Ames test and the SOS-chromotest.Mutat. Res. 322(4) , 321-8, (1994)
2-Chloroacrolein and 2-bromoacrolein are very potent direct mutagens not requiring metabolic activation in Salmonella typhimurium strains TA 100 and TA 1535. Mutagenic activities decrease with increas...
Formation of thymidine, cyclic deoxyguanosine and cyclic deoxycytidine adducts of the mutagen 2-bromoacrolein and their role in mutagenicity and clastogenicity.IARC Sci. Publ. (125) , 449-52, (1994)