FMOC-Arg(Pbf)-OH

Names

[ Name ]:
FMOC-Arg(Pbf)-OH

[Synonym ]:
Nalpha-Fmoc-Nomega-Pbf-L-arginine
Nα-Fmoc-Nω-Pbf-L-arginine
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-{N-[(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]carbamimidoyl}-L-ornithine
Na-Fmoc-Nw-Pbf-L-arginine
Fmoc-Arg(Pbf)-OH
(2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-5-{N'-[(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]carbamimidamido}pentanoic acid
MFCD00235804
L-Ornithine, N-[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
Fmoc-L-Arg(Pbf)-OH

Biological Activity

[Description]:

Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis)[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Beatriz G, et al. Successful development of a method for the incorporation of Fmoc-Arg (Pbf)-OH in solid-phase peptide synthesis using N-butylpyrrolidinone (NBP) as solvent. Green Chemistry, 2020, 22(10): 3162-3169.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Melting Point ]:
132°C

[ Molecular Formula ]:
C₃₄H₄₀N₄O₇S

[ Molecular Weight ]:
648.769

[ Exact Mass ]:
648.261780

[ PSA ]:
175.29000

[ LogP ]:
6.86

[ Index of Refraction ]:
1.649

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ HS Code ]:
2932999099

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Chemical synthesis of a polypeptide backbone derived from the primary sequence of the cancer protein NY-ESO-1 enabled by kinetically controlled ligation and pseudoprolines.

Biopolymers 104 , 116-27, (2015)

The cancer protein NY-ESO-1 has been shown to be one of the most promising vaccine candidates although little is known about its cellular function. Using a chemical protein strategy, the 180 amino aci...

A new class of peptidomimetics targeting the polo-box domain of Polo-like kinase 1.

J. Med. Chem. 58(1) , 294-304, (2015)

Recent progress in the development of peptide-derived Polo-like kinase (Plk1) polo-box domain (PBD) inhibitors has led to the synthesis of multiple peptide ligands with high binding affinity and selec...

Internalization of Near-Infrared Fluorescently Labeled Activatable Cell-Penetrating Peptide and of Proteins into Human Fibrosarcoma Cell Line HT-1080.

J. Cell. Biochem. 116 , 1222-31, (2015)

The internalization of near-infrared fluorescently labeled cargos into living cells and tissues allows a highly sensitive detection without interference from skin, porphins or other fluorescent cell a...

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.