Chlortoluron
Names
[ CAS No. ]:
15545-48-9
[ Name ]:
Chlortoluron
[Synonym ]:
Chlorotoluron
Methanol, 1-[(3-chloro-4-methylphenyl)imino]-1-(dimethylamino)-, (E)-
Urea, N'-(3-chloro-4-methylphenyl)-N,N-dimethyl-
N’-(3-chloro-4-methylphenyl)-N,N-dimethylurea
3-(3-Chloro-4-methylphenyl)-1,1-dimethylurea
MFCD00018275
Chlortoluron
3-(3-chloro-p-tolyl)-1,1-dimethylurea
EINECS 239-592-2
3-(3-Chloro-4-methyl)-1,1-dimethylurea
N'-(3-Chloro-4-methylphenyl)-N,N-dimethylcarbamimidic acid
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
345.9±52.0 °C at 760 mmHg
[ Melting Point ]:
147-148ºC
[ Molecular Formula ]:
C10H13ClN2O
[ Molecular Weight ]:
212.676
[ Flash Point ]:
163.0±30.7 °C
[ Exact Mass ]:
212.071640
[ PSA ]:
32.34000
[ LogP ]:
2.62
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.541
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YS7230000
- CHEMICAL NAME :
- Urea, 3-(3-chloro-p-tolyl)-1,1-dimethyl-
- CAS REGISTRY NUMBER :
- 15545-48-9
- BEILSTEIN REFERENCE NO. :
- 2647688
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C10-H13-Cl-N2-O
- MOLECULAR WEIGHT :
- 212.70
- WISWESSER LINE NOTATION :
- GR B1 EMVN1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1300 mg/m3
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 21 gm/kg/90D-C
- TOXIC EFFECTS :
- Behavioral - food intake (animal) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 2 gm/kg
- SEX/DURATION :
- female 4 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 10 mg/kg
- SEX/DURATION :
- male 50 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 58,353,1978
Safety Information
[ Symbol ]:
GHS08, GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H351-H361d-H410
[ Precautionary Statements ]:
P273-P281-P501
[ Hazard Codes ]:
Xn:Harmful;N:Dangerousfortheenvironment;
[ Risk Phrases ]:
R40;R50/53;R63
[ Safety Phrases ]:
S26-S36/37-S46-S60-S61-S16
[ RIDADR ]:
UN 3077
[ RTECS ]:
YS7230000
[ HS Code ]:
2924299035
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2924299035
[ Summary ]:
2924299035 2-chlorobenzaldehyde。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%
Articles
Environ. Toxicol. Chem. 30(3) , 622-31, (2011)
Rates of pesticide degradation in aquatic ecosystems often differ between those observed within laboratory studies and field trials. Under field conditions, a number of additional processes may well h...
Polymer monolith microextraction using poly(butyl methacrylate-co-1,6-hexanediol ethoxylate diacrylate) monolithic sorbent for determination of phenylurea herbicides in water samples.Talanta 147 , 199-206, (2015)
In this study, recently developed 1,6-hexanediol ethoxylate diacrylate (HEDA)-based polymeric monoliths were utilized as sorbents for efficient extraction of phenylurea herbicides (PUHs) from water sa...
Analysis of trace levels of pesticides in rainwater by SPME and GC-tandem mass spectrometry after derivatisation with PFBBr.Anal. Bioanal. Chem 387(1) , 359-68, (2007)
Solid-phase microextraction (SPME) was used for the analysis of some pesticides (bromoxynil, chlorotoluron, diuron, isoproturon, 2,4-MCPA, MCPP and 2,4-D) in rainwater after derivatisation with PFBBr ...