sodium borodeuteride

Names

[ Name ]:
sodium borodeuteride

[Synonym ]:
MFCD00003519
Deuterated sodium borohydride Sodium tetradeuterioboron
EINECS 239-764-7
Sodium tetradeuterioboron
Sodium borodeuteride
sodium,tetradeuterioboranuide
Sodium Borohydride-d4

Biological Activity

[Description]:

Sodium borodeuteride-d4 is the deuterium labeled Sodium borodeuteride[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Chemical & Physical Properties

[ Density]:
1.07

[ Melting Point ]:
300ºC

[ Molecular Formula ]:
BD₄Na

[ Molecular Weight ]:
41.85720

[ Exact Mass ]:
42.05550

[ Storage condition ]:
water-free area

[ Water Solubility ]:
Soluble in liquid ammonia, amines and pyridine.

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02, GHS05, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H260-H301-H311-H314

[ Precautionary Statements ]:
P223-P231 + P232-P280-P301 + P310-P370 + P378-P422

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
F:Highlyflammable;T:Toxic;

[ Risk Phrases ]:
R15;R25;R34

[ Safety Phrases ]:
S28-S36/37/39-S45-S7/8

[ RIDADR ]:
UN 1426 4.3/PG 1

[ WGK Germany ]:
3

[ Packaging Group ]:
I

[ Hazard Class ]:
4.3

Articles

Characterization and immunomodulatory activities of polysaccharides from Spirogyra neglecta (Hassall) Kützing.

Biosci. Biotechnol. Biochem. 79 , 1644-53, (2015)

Sulfated polysaccharides (SP) isolated from freshwater green algae, Spirogyra neglecta (Hassall) Kützing, and fractionated SPs were examined to investigate their molecular characteristics and immunomo...

Simultaneous gas-chromatographic urinary measurement of sugar probes to assess intestinal permeability: use of time course analysis to optimize its use to assess regional gut permeability.

Clin. Chim. Acta 442 , 24-32, (2015)

Measurement of intestinal permeability is important in several diseases but currently several methods are employed. We sought to: (1) develop a new GC based method to measure urinary mannitol, lactulo...

Profiling pneumococcal type 3-derived oligosaccharides by high resolution liquid chromatography-tandem mass spectrometry.

J. Chromatogr. A. 1397 , 43-51, (2015)

Pneumococcal type-3 polysaccharide (Pn3P) is considered a major target for the development of a human vaccine to protect against Streptococcus pneumoniae infection. Thus, it is critical to develop met...

Related Compounds

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