N-(2,4-DIMETHYLPHENYL)-3-(PHOSPHONOOXY)-2-NAPHTHALENECARBOXAMIDE

[ Density]:
1.419 g/cm3

[ Melting Point ]:
189-190ºC

[ Molecular Formula ]:
C₁₉H₁₈NO₅P

[ Molecular Weight ]:
371.32400

[ Exact Mass ]:
371.09200

[ PSA ]:
105.67000

[ LogP ]:
4.25340

[ Index of Refraction ]:
1.692

[ Storage condition ]:
20°C

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

Ratjadone C-mediated nuclear accumulation of HDAC4: implications on Runx2-induced osteoblast differentiation of C3H10T1/2 mesenchymal stem cells.

Z. Naturforsch., C, J. Biosci. 69(11-12) , 471-8, (2015)

Histone deacetylases (HDACs) are a group of enzymes that deacetylate ε-N-acetyl lysine residues of histone and non-histone proteins and play an important role in gene regulation. HDAC4, a class-IIa HD...

The calcium-sensing receptor mediates bone turnover induced by dietary calcium and parathyroid hormone in neonates.

J. Bone Miner Res. 26 , 1057-71, (2011)

We have investigated, in neonates, whether the calcium-sensing receptor (CaR) mediates the effects of dietary calcium on bone turnover and/or modulates parathyroid hormone (PTH)-induced bone turnover....

Endogenous PTH deficiency impairs fracture healing and impedes the fracture-healing efficacy of exogenous PTH(1-34).

PLoS ONE 6(7) , e23060, (2011)

Although the capacity of exogenous PTH1-34 to enhance the rate of bone repair is well established in animal models, our understanding of the mechanism(s) whereby PTH induces an anabolic response durin...

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