aminopyrene
Names
[ CAS No. ]:
1606-67-3
[ Name ]:
aminopyrene
[Synonym ]:
aminopyrene
Pyren-1-amine
pyrenylamine
Pyrene,amino
EINECS 216-521-3
1-Pyrenamine
Pyren-1-amin
1-aminopyrene
aminoantipyrene
pyren-1-ylamine
3-AMINOPYRENE
1-AMinopyrene 250MG
1-AMINOPYRENE PURUM
1-aminopyrrene
1-amino-pyrene
MFCD00004140
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
440.8±14.0 °C at 760 mmHg
[ Melting Point ]:
115-117 °C(lit.)
[ Molecular Formula ]:
C16H11N
[ Molecular Weight ]:
217.265
[ Flash Point ]:
246.2±15.4 °C
[ Exact Mass ]:
217.089142
[ PSA ]:
26.02000
[ LogP ]:
3.89
[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C
[ Index of Refraction ]:
1.905
[ Stability ]:
Stable. Incompatible with strong oxidizing agents.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UR2275000
- CHEMICAL NAME :
- 1-Pyrenamine
- CAS REGISTRY NUMBER :
- 1606-67-3
- BEILSTEIN REFERENCE NO. :
- 1875737
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 12
- MOLECULAR FORMULA :
- C16-H11-N
- MOLECULAR WEIGHT :
- 217.28
- WISWESSER LINE NOTATION :
- L666 B6 2AB PJ GZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1070 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >1 mL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- DNA repair
MUTATION DATA
- TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 40 mg/L
- REFERENCE :
- MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 2,23,1987
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H312
[ Precautionary Statements ]:
P280
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R21/22;R40
[ Safety Phrases ]:
S45-S36/37
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
UR2275000
[ HS Code ]:
2921499090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2921499090
[ Summary ]:
2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Nat. Commun. 6 , 7040, (2015)
Electrochemical energy-storage devices have the potential to be clean and efficient, but their current cost and performance limit their use in numerous transportation and stationary applications. Many...
A method for high-throughput, sensitive analysis of IgG Fc and Fab glycosylation by capillary electrophoresis.J. Immunol. Methods 417 , 34-44, (2015)
The N-glycan of the IgG constant region (Fc) plays a central role in tuning and directing multiple antibody functions in vivo, including antibody-dependent cellular cytotoxicity, complement deposition...
Biopartitioning micellar chromatography to predict mutagenicity of aromatic amines.Eur. J. Med. Chem. 42 , 1396-402, (2007)
Mutagenicity is a toxicity endpoint associated with the chronic exposure to chemicals. Aromatic amines have considerable industrial and environmental importance due to their widespread use in industry...