Diphenylacetyl chloride
Names
[ CAS No. ]:
1871-76-7
[ Name ]:
Diphenylacetyl chloride
[Synonym ]:
2,2-di(phenyl)acetyl chloride
2,2-di(phenyl)ethanoyl chloride
Diphenylacetyl chloride
Diphenylacetic acid chloride
EINECS 217-493-5
2,2-diphenylacetyl chloride
α,α-Diphenylacetyl chloride
Acetyl chloride,diphenyl
1,1-diphenylacetyl chloride
MFCD00013655
Benzeneacetyl chloride, α-phenyl-
2,2-diphenylethanoyl chloride
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
304.9±0.0 °C at 760 mmHg
[ Melting Point ]:
49-53 °C(lit.)
[ Molecular Formula ]:
C14H11ClO
[ Molecular Weight ]:
230.689
[ Flash Point ]:
154.9±18.0 °C
[ Exact Mass ]:
230.049850
[ PSA ]:
17.07000
[ LogP ]:
3.96
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.584
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AO6750000
- CHEMICAL NAME :
- Acetyl chloride, diphenyl-
- CAS REGISTRY NUMBER :
- 1871-76-7
- BEILSTEIN REFERENCE NO. :
- 1211588
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C14-H11-Cl-O
- MOLECULAR WEIGHT :
- 230.70
- WISWESSER LINE NOTATION :
- GVYR&R
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 6330 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Behavioral - ataxia
- REFERENCE :
- GNAMAP Gigiena Naselennykh Mest. Hygiene in Populated Places. (Izdatel'stvo Zdorov'ya, Kiev, USSR) V.7- 1967- Volume(issue)/page/year: 17,48,1978
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4700 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Behavioral - ataxia
- REFERENCE :
- GNAMAP Gigiena Naselennykh Mest. Hygiene in Populated Places. (Izdatel'stvo Zdorov'ya, Kiev, USSR) V.7- 1967- Volume(issue)/page/year: 17,48,1978 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 37980 mg/kg/26W-I
- TOXIC EFFECTS :
- Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Blood - changes in erythrocyte (RBC) count Related to Chronic Data - death
- REFERENCE :
- GNAMAP Gigiena Naselennykh Mest. Hygiene in Populated Places. (Izdatel'stvo Zdorov'ya, Kiev, USSR) V.7- 1967- Volume(issue)/page/year: 17,48,1978
Safety Information
[ Symbol ]:
GHS05, GHS07
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H314-H335
[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
C:Corrosive;
[ Risk Phrases ]:
R34;R36/37
[ Safety Phrases ]:
S26-S27-S28-S36/37/39-S45
[ RIDADR ]:
UN 3261 8/PG 2
[ WGK Germany ]:
2
[ RTECS ]:
AO6750000
[ Packaging Group ]:
II
[ Hazard Class ]:
8
[ HS Code ]:
29163900
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 29163900
Articles
Carbohydr. Res. 262(2) , 271-82, (1994)
Regioselective acylation of cyclomalto-oligosaccharides was achieved using pivaloyl and diphenylacetyl chlorides. The reaction of cyclomaltohexaose (1) with pivaloyl chloride gave the hexakis(2,6-di-O...
Synthesis and pharmacological screening of certain N-substituted amides structurally related to some local anesthetics.Pharmazie 34(1) , 12-3, (1979)
Diphenylacetyl chloride and pivaloyl chloride have been condensed with a wide variety of amines. Some of the resulting amides showed local anesthetic properties higher than those of procaine hydrochlo...