3-Methoxy-2-phenylethylamine
Names
[ CAS No. ]:
2039-67-0
[ Name ]:
3-Methoxy-2-phenylethylamine
[Synonym ]:
3-Methoxy-2-phenylethylamine
m-Methoxyphenethylamine
3-methoxy-benzeneethanamine
EINECS 218-017-9
Phenethylamine,m-methoxy
m-Methoxyphenylethylamine
3-methoxy-phenethylamine
2-(3-Methoxyphenyl)ethanamine
3-(2-Aminoethyl)anisole
Benzeneethanamine, 3-methoxy-
3-Methoxyphenylethylamine
MFCD00008187
3-Methoxy-β-phenethylamine
3-Methoxyphenethylamine
2-(3-Methoxyphenyl)ethylamine
Biological Activity
[Description]:
[Related Catalog]:
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
262.7±0.0 °C at 760 mmHg
[ Molecular Formula ]:
C9H13NO
[ Molecular Weight ]:
151.206
[ Flash Point ]:
104.9±13.6 °C
[ Exact Mass ]:
151.099716
[ PSA ]:
35.25000
[ LogP ]:
1.37
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.526
[ Water Solubility ]:
Insoluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SH7835000
- CHEMICAL NAME :
- Phenethylamine, m-methoxy-
- CAS REGISTRY NUMBER :
- 2039-67-0
- BEILSTEIN REFERENCE NO. :
- 0775202
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C9-H13-N-O
- MOLECULAR WEIGHT :
- 151.23
- WISWESSER LINE NOTATION :
- Z2R CO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 230 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement Lungs, Thorax, or Respiration - respiratory stimulation
- REFERENCE :
- JPHYA7 Journal of Physiology. (Cambridge Univ. Press, 32 E. 57th St., New York, NY 10022) V.1- 1878- Volume(issue)/page/year: 76,224,1932
Safety Information
[ Symbol ]:
GHS05
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H314
[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
C:Corrosive;
[ Risk Phrases ]:
R34
[ Safety Phrases ]:
S26-S36/37/39-S45
[ RIDADR ]:
UN 2735 8/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
SH7835000
[ Hazard Class ]:
8.0
[ HS Code ]:
2922299090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922299090
[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Biochemistry 40 , 14215, (2001)
Cytochrome P450 (P450) 2D6 oxidizes a wide variety of drugs typically at a distance of 5-7 A from a basic nitrogen on the substrate. To investigate the determinants of P450 2D6 catalysis, we analyzed ...
A microdialysis study on striatal dopamine, 5-HT and metabolites in conscious rats after various treatments: evidence for extravesicular release of dopamine.Neuroreport 5(1) , 53-6, (1993)
The effects of death and various treatments that affect the status of nigrostriatal neurones on striatal release of dopamine (DA) and 5-hydroxytryptamine (5-HT) and their metabolites 3,4-dihydroxyphen...
Structure–activity correlations for β-phenethylamines at human trace amine receptor 1Bioorg. Med. Chem. 16 , 7415-23, (2008)
CoMFA 3D-QSAR studies on the potency of 68 β-phenethylamine analogs to activate hTAAR 1 (61% steric, 39% electrostatic) indicates that bulk both at nitrogen and 4-aryl leads to lower potency.