pcb 1
Names
[ CAS No. ]:
2051-60-7
[ Name ]:
pcb 1
[Synonym ]:
O-CHLOROBIPHENYL
PCB No 1,2-PCB
2-Chlorobiphenyl
2-PCB
chlorobiphenyl
2-Chlorodiphenyl
PCB NO 1
2-chloro-bipheny
2-chloro-1,1'-biphenyl
BZNO 1
EINECS 218-125-6
mono-chlorobiphenyl
MFCD00013626
1,1'-Biphenyl, 2-chloro-
pcb 1
2-chloro-biphenyl
o-Cl-C6H4-Ph
O-CHLORODIPHENYL
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
274.0±9.0 °C at 760 mmHg
[ Melting Point ]:
32-34ºC
[ Molecular Formula ]:
C12H9Cl
[ Molecular Weight ]:
188.653
[ Flash Point ]:
115.9±8.6 °C
[ Exact Mass ]:
188.039276
[ LogP ]:
4.45
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.583
[ Stability ]:
Stable. Incompatible with strong oxidizing agents.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DV2065000
- CHEMICAL NAME :
- Biphenyl, 2-chloro-
- CAS REGISTRY NUMBER :
- 2051-60-7
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C12-H9-Cl
- MOLECULAR WEIGHT :
- 188.66
- WISWESSER LINE NOTATION :
- GR BR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 2500 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- JIDHAN Journal of Industrial Hygiene. (Cambridge, MA) V.1-17, 1919-35. For publisher information, see AEHLAU. Volume(issue)/page/year: 13,87,1931 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 150 mg/kg/3D-I
- TOXIC EFFECTS :
- Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other esterases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other hydrolases
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 33,94,1975
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 25 mg/kg/20D-I
- TOXIC EFFECTS :
- Liver - other changes
- REFERENCE :
- JEPOEC Journal of Environmental Pathology, Toxicology and Oncology. (Chem-Orbital, POB 134, Park Forest, IL 60466) V.5(4)- 1984- Volume(issue)/page/year: 12,17,1993
Safety Information
[ Symbol ]:
GHS08, GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H373-H410
[ Precautionary Statements ]:
P273-P391-P501
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;N: Dangerous for the environment;
[ Risk Phrases ]:
R33
[ Safety Phrases ]:
35-60-61
[ RIDADR ]:
3077
[ RTECS ]:
DV2065000
[ Packaging Group ]:
III
[ Hazard Class ]:
9
[ HS Code ]:
2903999090
Synthetic Route
Customs
[ HS Code ]: 2903999090
[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%
Articles
Eur. J. Med. Chem. 43 , 714-40, (2008)
Simplified molecular input line entry system (SMILES) has been utilized in constructing quantitative structure-property relationships (QSPR) for octanol/water partition coefficient of vitamins and org...
Sphingobium fuliginis HC3: a novel and robust isolated biphenyl- and polychlorinated biphenyls-degrading bacterium without dead-end intermediates accumulation.PLoS ONE 10(4) , e0122740, (2015)
Biphenyl and polychlorinated biphenyls (PCBs) are typical environmental pollutants. However, these pollutants are hard to be totally mineralized by environmental microorganisms. One reason for this is...
Quantitative structure-activity relationship analysis of inhibitors of the nicotine metabolizing CYP2A6 enzyme.J. Med. Chem. 48 , 440-9, (2005)
The purpose of this study was to develop screening and in silico modeling methods to obtain accurate information on the active center of CYP2A6, a nicotine oxidizing enzyme. The inhibitory potencies o...