5-Chlorooxindole
Names
[ CAS No. ]:
25369-33-9
[ Name ]:
5-Chlorooxindole
[Synonym ]:
7-CHLORO-1,3-DIHYDRO-2H-INDOL-2-ONE
5-Chlorooxindole
2H-Indol-2-one, 5-chloro-1,3-dihydro-
7-chloro-1,3-dihydroindol-2-one
5-chloroindolin-2-one
5-Chloro-1,3-dihydro-2H-indol-2-one
2H-Indol-2-one, 7-chloro-1,3-dihydro-
7-Chloroindolin-2-one
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
341.0±42.0 °C at 760 mmHg
[ Melting Point ]:
221-225ºC
[ Molecular Formula ]:
C8H6ClNO
[ Molecular Weight ]:
167.592
[ Flash Point ]:
160.0±27.9 °C
[ Exact Mass ]:
167.013794
[ PSA ]:
29.10000
[ LogP ]:
1.35
[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C
[ Index of Refraction ]:
1.602
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H319
[ Precautionary Statements ]:
P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
R22
[ Safety Phrases ]:
61
[ RIDADR ]:
NONH for all modes of transport
[ HS Code ]:
2933790090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933790090
[ Summary ]:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%
Articles
J. Pharm. Biomed. Anal. 14(7) , 825-33, (1996)
5-Chlorooxindole (5-CO) is a starting material for tenidap sodium, a pharmaceutical drug candidate produced by Pfizer. To insure potency and purity of the drug substance, it is necessary to demonstrat...