4,4′-Thiodiphenol
Names
[ CAS No. ]:
2664-63-3
[ Name ]:
4,4′-Thiodiphenol
[Synonym ]:
Bis(4-hydroxyphenyl) sulfide
Thiobisphenol
4,4'-Thiobisphenol
MFCD00002349
Phenol, 4,4'-thiobis-
4-(4-hydroxyphenyl)sulfanylphenol
4-hydroxyphenyl sulphide
p,p'-Dihydroxydiphenyl sulfide
4,4′-Thiodiphenol
4,4'-thiodiphenol
4,4'-Thiobis-phenol
4,4'-dihydroxyldiphenyl sulfide
4,4'-Sulfanediyldiphenol
4,4'-Dihydroxydiphenyl sulfide
4,4-Thiodiphenol
EINECS 220-197-9
Phenol,4,4'-thiobis
4,4'-Dihydroxy diphenyl sulfide
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
452.7±30.0 °C at 760 mmHg
[ Melting Point ]:
154-156 °C(lit.)
[ Molecular Formula ]:
C12H10O2S
[ Molecular Weight ]:
218.272
[ Flash Point ]:
219.7±23.3 °C
[ Exact Mass ]:
218.040146
[ PSA ]:
65.76000
[ LogP ]:
3.34
[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C
[ Index of Refraction ]:
1.717
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SN0800000
- CHEMICAL NAME :
- Phenol, 4,4'-thiodi-
- CAS REGISTRY NUMBER :
- 2664-63-3
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C12-H10-O2-S
- MOLECULAR WEIGHT :
- 218.28
- WISWESSER LINE NOTATION :
- QR DSR DQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. (1810 Frontage Rd., Northbrook, IL 60062) Volume(issue)/page/year: A408,1971
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. (1810 Frontage Rd., Northbrook, IL 60062) Volume(issue)/page/year: A408,1971 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3362 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. (1810 Frontage Rd., Northbrook, IL 60062) Volume(issue)/page/year: A408,1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 13,154,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >10250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. (1810 Frontage Rd., Northbrook, IL 60062) Volume(issue)/page/year: A408,1971 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 3 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0044 No. of Facilities: 69 (estimated) No. of Industries: 3 No. of Occupations: 3 No. of Employees: 1146 (estimated)
Safety Information
[ Symbol ]:
GHS05
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H314
[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
C:Corrosive;
[ Risk Phrases ]:
R34
[ Safety Phrases ]:
S26-S27-S36/37/39-S45
[ RIDADR ]:
UN 3261 8/PG 2
[ WGK Germany ]:
2
[ RTECS ]:
SN0800000
[ Packaging Group ]:
II
[ Hazard Class ]:
8
[ HS Code ]:
29309070
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 29309070
Articles
Toxicol. In Vitro 29(1) , 8-15, (2014)
A homeostasis of the glucocorticoid and androgen endocrine system is essential to human health. Their disturbance can lead to various diseases, for example cardiovascular, inflammatory and autoimmune ...
[Materials for the establishment of maximum allowable concentrations of bis (4-oxyphenyl) sulfide in the working zone air].Gig. Tr. Prof. Zabol. (1) , 31-2, (1991)