spermine tetrahydrochloride
Names
[ CAS No. ]:
306-67-2
[ Name ]:
spermine tetrahydrochloride
[Synonym ]:
N,N'-Bis(3-aMinopropyl)-1,4-butanediaMine Tetrahydrochloride
EINECS 206-189-8
N1,N1'-(Butane-1,4-diyl)bis(propane-1,3-diamine) tetrahydrochloride
Spermine tetrahydrochloride
N-(2-Aminoethyl)-N'-(3-aminopropyl)-1,4-butanediamine tetrahydrochloride
1,5,10,14-tetraazoniatetradecane tetrachloride
Additive Screening
Spermine hydrochloride
Geontine Tetrahydrochloride
Spermine tetrahydrochloride 0.1 M
1,4-Butanediamine, N-(2-aminoethyl)-N-(3-aminopropyl)-, hydrochloride (1:4)
Musculamine tetrahydrochloride
MFCD00012914
Neuridine tetrahydrochloride
Spm tetrahydrochloride
Gerontine tetrahydrochloride
Chemical & Physical Properties
[ Density]:
1.01 g/mL at 20 °C
[ Boiling Point ]:
308.4ºC at 760mmHg
[ Melting Point ]:
310-311 °C (dec.)(lit.)
[ Molecular Formula ]:
C10H30Cl4N4
[ Molecular Weight ]:
334.157
[ Flash Point ]:
175.6ºC
[ Exact Mass ]:
332.106812
[ PSA ]:
76.10000
[ LogP ]:
5.03380
[ Appearance of Characters ]:
powder
[ Storage condition ]:
2-8°C
[ Water Solubility ]:
H2O: 1 M at 20 °C, clear, colorless
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- EJ7230000
- CHEMICAL NAME :
- 1,4-Butanediamine, N,N'-bis(3-aminopropyl)-, tetrahydrochloride
- CAS REGISTRY NUMBER :
- 306-67-2
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C10-H26-N4.4Cl-H
- MOLECULAR WEIGHT :
- 348.24
- WISWESSER LINE NOTATION :
- Z3M4M3Z 4GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 370 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - other changes
MUTATION DATA
- TYPE OF TEST :
- DNA adduct
- TEST SYSTEM :
- Mammal - species unspecified Lymphocyte
- DOSE/DURATION :
- 16700 nmol/L
- REFERENCE :
- BIPMAA Biopolymers. (John Wiley & Sons, Inc., 605 Third Ave., New York, NY 10158) V.1- 1963- Volume(issue)/page/year: 5,227,1967
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319
[ Precautionary Statements ]:
P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
EJ7230000
[ HS Code ]:
2921290000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2921290000
[ Summary ]:
2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
Articles
Org. Biomol. Chem. 13 , 7500-12, (2015)
Within all the eukaryotic cells myo-inositol phosphates (InsPs) are an important group of biomolecules that are potentially related to signaling functions. The most abundant member of this family in n...
An Extended-gate Type Organic FET Based Biosensor for Detecting Biogenic Amines in Aqueous Solution.Anal. Sci. 31 , 721-4, (2015)
This study is the first to report on the detection of biogenic amines in an aqueous solution using an organic field-effect transistor (OFET) device with an extended gate electrode modified with a laye...
Effect of Novel Starter Culture on Reduction of Biogenic Amines, Quality Improvement, and Sensory Properties of Doenjang, a Traditional Korean Soybean Fermented Sauce Variety.J. Food Sci. 80 , M1794-803, (2015)
To select appropriate microorganisms as starter cultures for the reliable and reproducible fermentation of soybean fermented products of Korean Doenjang, various ratios of fungi (Aspergillus oryzae J,...