UNII:43B0856528
Names
[ CAS No. ]:
4098-71-9
[ Name ]:
UNII:43B0856528
[Synonym ]:
3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl Isocyanate
5-Isocyanato-1-(isocyanatomethyl)-1,3,3-trimethylcyclohexane
Isophorone diisocyanate
Cyclohexane, 5-isocyanato-1-(isocyanatomethyl)-1,3,3-trimethyl-
EINECS 223-861-6
UNII:43B0856528
MFCD00064956
IPDI
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
286.9±13.0 °C at 760 mmHg
[ Melting Point ]:
-60°C
[ Molecular Formula ]:
C12H18N2O2
[ Molecular Weight ]:
222.283
[ Flash Point ]:
116.0±25.2 °C
[ Exact Mass ]:
222.136826
[ PSA ]:
58.86000
[ LogP ]:
4.67
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.520
[ Stability ]:
Reacts with all substances containing active hydrogen, such as acids, amines, water, phenols, mercaptans, amides, urea. Probably moisture sensitive.
[ Water Solubility ]:
<0.1 g/100 mL at 25 ºC
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NQ9370000
- CHEMICAL NAME :
- Isocyanic acid, methylene(3,5,5-trimethyl-3,1-cyclohexylene) ester
- CAS REGISTRY NUMBER :
- 4098-71-9
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 24
- MOLECULAR FORMULA :
- C12-H18-N2-O2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4825 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0530238
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 123 mg/m3/4H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85INA8 "Documentation of the Threshold Limit Values and Biological Exposure Indices," 5th ed., Cincinnati, OH, American Conference of Governmental Industrial Hygienists, Inc., 1986 Volume(issue)/page/year: 5,334(86),1986
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1 mL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0528418
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2500 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0528418
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 1 mL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0528418
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 118 mg/m3/1H
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0543418 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1370 ug/m3/4H/4W-I
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0528418 *** REVIEWS *** ACGIH TLV-TWA 0.045 mg/m3 (0.005 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-BELGIUM:TWA 0.005 ppm (0.045 mg/m3);Skin JAN 1993 OEL-DENMARK:TWA 0.005 ppm (0.045 mg/m3);Skin JAN 1993 OEL-FRANCE:TWA 0.010 ppm (0.09 mg/m3);STEL 0.020 ppm JAN 1993 OEL-GERMANY:TWA 0.01 ppm (0.09 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 0.01 ppm (0.09 mg/m3);Skin JAN 1993 OEL-SWEDEN:TWA 0.005 ppm (0.05 mg/m3);STEL 0.01 ppm (0.09 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 0.01 ppm (0.09 mg/m3);STEL 0.02 ppm JAN 1993 OEL-UNITED KINGDOM:TWA 0.02 mg/m3;STEL 0.07 mg/m3 JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO IPDI-air:10H TWA 0.005 ppm (Sk);STEL 0.02 ppm (Sk) REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83571 No. of Facilities: 111 (estimated) No. of Industries: 4 No. of Occupations: 19 No. of Employees: 3441 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83571 No. of Facilities: 1186 (estimated) No. of Industries: 15 No. of Occupations: 16 No. of Employees: 7245 (estimated) No. of Female Employees: 682 (estimated)
Safety Information
[ Symbol ]:
GHS06, GHS08, GHS09
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H315-H317-H319-H330-H334-H335-H411
[ Precautionary Statements ]:
P260-P280-P284-P304 + P340 + P310-P342 + P311-P403 + P233
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
T:Toxic;N:Dangerousfortheenvironment;
[ Risk Phrases ]:
R22;R36/37/38;R42/43;R51/53
[ Safety Phrases ]:
S26-S28-S38-S45-S61
[ RIDADR ]:
UN 2290 6.1/PG 3
[ WGK Germany ]:
2
[ RTECS ]:
NQ9370000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
[ HS Code ]:
2929109000
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2929109000
[ Summary ]:
2929109000. other isocyanates. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
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