3,4-Diaminotoluene
Names
[ CAS No. ]:
496-72-0
[ Name ]:
3,4-Diaminotoluene
[Synonym ]:
1,2-Benzenediamine, 4-methyl-
3,4-toluenediamine
EINECS 207-826-2
4-Methyl-1,2-benzenediamine
4-methylbenzene-1,2-diamine
MFCD00007728
3,4-Diaminotoluene
Tolylene-3,4-diamine
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
262.3±20.0 °C at 760 mmHg
[ Melting Point ]:
87-89 °C(lit.)
[ Molecular Formula ]:
C7H10N2
[ Molecular Weight ]:
122.168
[ Flash Point ]:
132.1±21.3 °C
[ Exact Mass ]:
122.084396
[ PSA ]:
52.04000
[ LogP ]:
0.51
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.636
[ Stability ]:
Stable. Incompatible with strong oxidizing agents.
[ Water Solubility ]:
16 g/L (20 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XS9820000
- CHEMICAL NAME :
- Toluene-3,4-diamine
- CAS REGISTRY NUMBER :
- 496-72-0
- BEILSTEIN REFERENCE NO. :
- 0507965
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C7-H10-N2
- MOLECULAR WEIGHT :
- 122.19
- WISWESSER LINE NOTATION :
- ZR BZ D1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- Micronucleus test
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 91,75,1981
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302 + H312 + H332-H315-H319-H335
[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn:Harmful
[ Risk Phrases ]:
R22;R36;R40;R52/53
[ Safety Phrases ]:
S26-S37/39-S61-S36/37/39
[ RIDADR ]:
UN 2811
[ WGK Germany ]:
2
[ RTECS ]:
XS9820000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)
[ HS Code ]:
29215119
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2921590090
[ Summary ]:
2921590090. other aromatic polyamines and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Teratology 24(3) , 253-65, (1981)
Pregnant outbred albino (CD-1) mice were given 2-nitro-p-phenylenediamine (2NPPD; 32-256 mg/kg/day), 4-nitro-o-phenylenediamine (4NOPD; 16-1024 mg/kg/day) or 2,5-toluenediamine sulfate (2,5TDS; 16-64 ...
Effect of 4 toluene diamine isomers on murine testicular DNA synthesis.Mutat. Res. 91(1) , 75-9, (1981)
Teratogenesis study of o-toluenediamine in rats and rabbits.
Toxicol. Appl. Pharmacol. 71(3) , 323-9, (1983)
o-Toluenediamine in corn oil was administered po to Sprague-Dawley rats at dosages of 10, 30, 100, or 300 mg/kg body wt/day during Days 6 through 15 of gestation. All animals were killed on Day 20 of ...