2,4,6-Trichlorobenzoic acid
Names
[ CAS No. ]:
50-43-1
[ Name ]:
2,4,6-Trichlorobenzoic acid
[Synonym ]:
2,4,6-Trichlor-benzoesaeure
2,4,6-trichlorbenzoes
2,4,6-trichlorophenylcarboxylic acid
Benzoic acid, 2,4,6-trichloro-
2,3-DIHYDROBENZO[B]FURAN-5-CARBOXALDEHYDE O5-ETHYLOXIME
2,4,6-Trichlorobenzoicacid
2,4,6-Trichlorobenzoic acid
Benzoic acid,2,4,6-trichloro
MFCD00060699
Chemical & Physical Properties
[ Density]:
1.6±0.1 g/cm3
[ Boiling Point ]:
329.7±37.0 °C at 760 mmHg
[ Melting Point ]:
160-164 °C(lit.)
[ Molecular Formula ]:
C7H3Cl3O2
[ Molecular Weight ]:
225.456
[ Flash Point ]:
153.2±26.5 °C
[ Exact Mass ]:
223.919861
[ PSA ]:
37.30000
[ LogP ]:
2.98
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.611
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DH8050000
- CHEMICAL NAME :
- Benzoic acid, 2,4,6-trichloro-
- CAS REGISTRY NUMBER :
- 50-43-1
- BEILSTEIN REFERENCE NO. :
- 1874127
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C7-H3-Cl3-O2
- MOLECULAR WEIGHT :
- 225.45
- WISWESSER LINE NOTATION :
- QVR BG DG FG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1200 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 13,1538,1964
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
DH8050000
[ HS Code ]:
2916399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2916399090
[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Environ. Monit. Assess. 187(1) , 4170, (2015)
Chlorobenzoic acids represent crucial recalcitrant metabolites in the environment; thus, the influence of soil components on the sorption of 2,4,6-trichlorobenzoic acid (TCB) under oxic and anoxic con...
Phenoxy herbicides and fibrates potently inhibit the human chemosensory receptor subunit T1R3.J. Med. Chem. 52 , 6931-5, (2009)
We show that phenoxyauxin herbicides and lipid-lowering fibrates inhibit human but not rodent T1R3. T1R3 as a coreceptor in taste cells responds to sweet compounds and amino acids; in endocrine cells ...
Impact of nutrient composition on a degradative biofilm community.Appl. Environ. Microbiol. 63(6) , 2432-8, (1997)
A microbial community was cultivated in flow cells with 2,4,6-trichlorobenzoic acid (2,4,6-TCB) as sole carbon and energy source and was examined with scanning confocal laser microscopy and fluorescen...