2,5-Dichlorobenzoic acid
Names
[ CAS No. ]:
50-79-3
[ Name ]:
2,5-Dichlorobenzoic acid
[Synonym ]:
2,5-dichlorobenzoicacid
MFCD00002416
RARECHEM AL BO 0355
EINECS 200-065-7
3-fluoro-4-nitrobenzoic acide
5-Dichlorobenzoic acid
1,2-DICHLOROBENZENE PESTANAL
2,5-Dichlorobenzoic acid
2,4-DIETHOXY BENZALDEHYDE
Benzoic acid, 2,5-dichloro-
2,5-dichloro-benzoicaci
2,5-DBA
Benzoic acid,2,5-dichloro
2,5-Dichlor-benzoesaeure
Irsogladine Impurity 2
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Boiling Point ]:
301.0±22.0 °C at 760 mmHg
[ Melting Point ]:
151-154 °C(lit.)
[ Molecular Formula ]:
C7H4Cl2O2
[ Molecular Weight ]:
191.012
[ Flash Point ]:
135.8±22.3 °C
[ Exact Mass ]:
189.958832
[ PSA ]:
37.30000
[ LogP ]:
2.97
[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C
[ Index of Refraction ]:
1.599
[ Stability ]:
Stable.
[ Water Solubility ]:
<0.1 g/100 mL at 19 ºC
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DG6825000
- CHEMICAL NAME :
- Benzoic acid, 2,5-dichloro-
- CAS REGISTRY NUMBER :
- 50-79-3
- BEILSTEIN REFERENCE NO. :
- 0973353
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C7-H4-Cl2-O2
- MOLECULAR WEIGHT :
- 191.01
- WISWESSER LINE NOTATION :
- QVR BG EG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1200 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 237 mg/kg
- TOXIC EFFECTS :
- Behavioral - rigidity (including catalepsy) Behavioral - muscle contraction or spasticity
MUTATION DATA
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 1 gm/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 264,1,1991
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
DG6825000
[ HS Code ]:
2916399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2916399090
[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Mikrobiologiia 62(5) , 887-96, (1993)
The strain Pseudomonas aeruginosa 142 isolated from the utilising PSBs bacterial association was capable of growth on 2-chloro- and 2,4-dichlorobenzoates as sole carbon sources, but it did not utilize...
Degradation of 2,5-dichlorobenzoic acid by Pseudomonas aeruginosa JB2 at low oxygen tensions.Biodegradation 6(1) , 39-46, (1995)
From long-term chemostat experiments, variants of Pseudomonas aeruginosa JB2 were obtained which exhibited altered properties with respect to the metabolism of 2,5-dichlorobenzoic acid (2,5-DBA). Thus...
Quantitation in gradient high performance liquid chromatography/inductively coupled mass spectrometry investigated using diclofenac and chlorpromazine.Rapid Commun. Mass Spectrom. 16(4) , 245-7, (2002)
The use of directly coupled high performance liquid chromatography/inductively coupled plasma mass spectroscopy (HPLC/ICPMS) employing chlorine ((35)Cl/(37)Cl) detection has been investigated with res...