|p|-Aminophenol hydrochloride
Names
[ CAS No. ]:
51-78-5
[ Name ]:
|p|-Aminophenol hydrochloride
[Synonym ]:
4-Aminophenol hydrochloride
EINECS 200-122-6
p-Aminophenol hydrochloride
4-Hydroxyaniline hydrochloride
MFCD00012996
Chemical & Physical Properties
[ Density]:
1.21g/cm3
[ Boiling Point ]:
282ºC at 760mmHg
[ Melting Point ]:
302 °C
[ Molecular Formula ]:
C6H8ClNO
[ Molecular Weight ]:
145.58700
[ Flash Point ]:
124.3ºC
[ Exact Mass ]:
145.02900
[ PSA ]:
46.25000
[ LogP ]:
2.35760
[ Stability ]:
Stable, but hygroscopic, air and light sensitive. Incompatible with strong oxidizing agents.
[ Water Solubility ]:
soluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SJ6070000
- CHEMICAL NAME :
- Phenol, p-amino-, hydrochloride
- CAS REGISTRY NUMBER :
- 51-78-5
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C6-H7-N-O.Cl-H
- MOLECULAR WEIGHT :
- 145.60
- WISWESSER LINE NOTATION :
- ZR DQ &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 750 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TEST SYSTEM :
- Insect - Drosophila melanogaster
- DOSE/DURATION :
- 20 mmol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 240,87,1990 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1445 No. of Facilities: 3 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 198 (estimated) No. of Female Employees: 151 (estimated)
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H317-H319-H335
[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38;R43
[ Safety Phrases ]:
S28-S36
[ RIDADR ]:
2811.0
[ WGK Germany ]:
3
[ RTECS ]:
SJ6070000
[ Packaging Group ]:
I; II; III
[ Hazard Class ]:
6.1
[ HS Code ]:
29222900
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922299090
[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
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Herein, we report the preparation of poly (cyclotriphosphazene-co-4,4'-sulfonyldiphenol) (PZS) nanotubes decorated with Ag nanoparticles (NPs). The PZS nanotubes have been synthesized firstly via an i...
Cellular apoptosis and cytotoxicity of phenolic compounds: a quantitative structure-activity relationship study.J. Med. Chem. 48 , 7234-42, (2005)
In this comprehensive study on the caspase-mediated apoptosis-inducing effect of 51 substituted phenols in a murine leukemia cell line (L1210), we determined the concentrations needed to induce caspas...
Amine-functionalized polyglycidyl methacrylate microsphere as a unified template for the synthesis of gold nanoparticles and single-crystal gold plates.Macromol. Rapid Commun. 34(6) , 504-10, (2013)
Polyglycidyl methacrylate (PGMA) microspheres, crosslinked and surface-functionalized by amine, can be used as a solid-state template for the synthesis of gold (Au) crystals in the forms of either nan...