(L)-Canavanine
Names
[ CAS No. ]:
543-38-4
[ Name ]:
(L)-Canavanine
[Synonym ]:
L-Canavanine
L-α-AMINO-γ-[GUANIDINOOXY]-N-BUTYRIC ACID
Biological Activity
[Description]:
[Related Catalog]:
Chemical & Physical Properties
[ Density]:
1.61g/cm3
[ Boiling Point ]:
431.2ºC at 760mmHg
[ Melting Point ]:
184ºC
[ Molecular Formula ]:
C5H12N4O3
[ Molecular Weight ]:
176.17
[ Flash Point ]:
214.6ºC
[ Exact Mass ]:
176.09100
[ PSA ]:
134.45000
[ LogP ]:
0.09430
[ Index of Refraction ]:
1.602
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- ES7002000
- CHEMICAL NAME :
- Butyric acid, 2-amino-4-(guanidinooxy)-, L-
- CAS REGISTRY NUMBER :
- 543-38-4
- LAST UPDATED :
- 199410
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C5-H12-N4-O3
- MOLECULAR WEIGHT :
- 176.21
- WISWESSER LINE NOTATION :
- QVYZ2OMYZUM
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 7 gm/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5900 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - muscle contraction or spasticity
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Rodent - hamster Cells - not otherwise specified
- DOSE/DURATION :
- 2200 umol/L
- REFERENCE :
- JCLLAX Journal of Cellular Physiology. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.67- 1966- Volume(issue)/page/year: 75,129,1970
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H312-H332
[ Precautionary Statements ]:
P280
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
20/21/22
[ RIDADR ]:
NONH for all modes of transport
[ RTECS ]:
ES7002000
[ HS Code ]:
2925290090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2925290090
[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
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