2-Amino-1-phenylethanone hydrochloride
Names
[ CAS No. ]:
5468-37-1
[ Name ]:
2-Amino-1-phenylethanone hydrochloride
[Synonym ]:
EINECS 226-787-2
Ethanone, 2-amino-1-phenyl-, hydrochloride (1:1)
2-Amino-1-phenylethanone hydrochloride (1:1)
2-amino-1-phenylethanone,hydrochloride
MFCD00012873
Chemical & Physical Properties
[ Density]:
1.084g/cm3
[ Boiling Point ]:
247.3ºC at 760mmHg
[ Melting Point ]:
194 °C (dec.)(lit.)
[ Molecular Formula ]:
C8H10ClNO
[ Molecular Weight ]:
171.624
[ Flash Point ]:
103.4ºC
[ Exact Mass ]:
171.045090
[ PSA ]:
43.09000
[ LogP ]:
2.33030
[ Storage condition ]:
Refrigerator (+4°C)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AM5940000
- CHEMICAL NAME :
- Acetophenone, 2-amino-, hydrochloride
- CAS REGISTRY NUMBER :
- 5468-37-1
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C8-H9-N-O.Cl-H
- MOLECULAR WEIGHT :
- 171.64
- WISWESSER LINE NOTATION :
- Z1VR &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 350 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 9,203,1936
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S37/39-S26
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
AM5940000
[ HS Code ]:
2922399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922399090
[ Summary ]:
2922399090 other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Arch. Farmacol. Toxicol. 5(3) , 165-8, (1979)
Determination of cathinone, cathine and norephedrine in hair of Yemenite khat chewers.
Forensic Sci. Int. 133(1-2) , 39-46, (2003)
A sensitive and reproducible method for the quantitative determination of cathinone (CTN), norpseudoephedrine (NPE, cathine) and norephedrine (NE) from hair was developed. The compounds were extracted...
Mechanism-based inactivation of dopamine beta-monooxygenase by beta-chlorophenethylamine.J. Biol. Chem. 259(12) , 7772-9, (1984)
Functionalization of the beta-carbon of phenethylamines has been shown to produce a new class of substrate/inhibitor of dopamine beta-monooxygenase. Whereas both beta-hydroxy- and beta- chlorophenethy...