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cymoxanil

Names

[ CAS No. ]:
57966-95-7

[ Name ]:
cymoxanil

[Synonym ]:
Cymoxanil
1-[(EZ)-2-cyano-2-methoxyiminoacetyl]-3-ethylurea
CURZATE
cymoxyanil
dpx3217m
PULSAN
RIFLE XG
(2Ξ)-2-cyano-N-(ethylcarbamoyl)-2-(methoxyimino)acetamide
1-(2-Cyano-2-methoxyiminoacetyl)-3-ethylurea
2MVMVYCN&UNO1
EINECS 261-043-0
MANEX C-8
MFCD00137381
2-Cyano-N-[(ethylamino)carbonyl]-2-(methoxyimino)acetamide
CIMOXPRON
Acetamide, 2-cyano-N-[(ethylamino)carbonyl]-2-(methoxyimino)-
2-Cyano-N-(ethylcarbamoyl)-2-(methoxyimino)acetamide
cymoxanil [ANSI]
DPX 3217

Biological Activity

[Description]:

Cymoxanil is a fungicidal against plant diseases caused by fungi belonging to the Perenosporales[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Fungal

[Target]

Fungal[1]


[References]

[1]. Frederique Tellier , et al. Characterization of Metabolites of Fungicidal Cymoxanil in a Sensitive Strain of Botrytis Cinerea. J Agric Food Chem. 2008 Sep 10;56(17):8050-7.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Melting Point ]:
160-161ºC

[ Molecular Formula ]:
C7H10N4O3

[ Molecular Weight ]:
198.179

[ Flash Point ]:
100 °C

[ Exact Mass ]:
198.075287

[ PSA ]:
103.58000

[ LogP ]:
0.67

[ Index of Refraction ]:
1.537

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AB5957000
CHEMICAL NAME :
Acetamide, 2-cyano-N-((ethylamino)carbonyl)-2-(methoxyimino)-
CAS REGISTRY NUMBER :
57966-95-7
LAST UPDATED :
199710
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C7-H10-N4-O3
MOLECULAR WEIGHT :
198.21
WISWESSER LINE NOTATION :
2MVMVYCN&UNO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C90,1991
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4980 mg/m3/4H
TOXIC EFFECTS :
Behavioral - general anesthetic Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533649-1
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
1500 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0570815
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A102,1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 35,179,1981
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
1096 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,206,1991

Safety Information

[ Symbol ]:

GHS07, GHS08, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H317-H361fd-H373-H410

[ Precautionary Statements ]:
P201-P273-P280-P308 + P313-P333 + P313-P391

[ Target Organs ]:
Blood, thymus

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R43;R50/53

[ Safety Phrases ]:
S36/37-S60-S61

[ RIDADR ]:
UN 3077

[ RTECS ]:
AB5957000

[ HS Code ]:
2926909038

Precursor & DownStream

Customs

[ HS Code ]: 2926909038

[ Summary ]:
HS: 2926909038 fenoxanil Educational tariff:17.0% Tax rebate rate:9.0% Regulatory conditions:S(Registration certificate of import and export) Lowest tariff:6.5% General tariff:30.0%

Articles

Dissipation and residue of metalaxyl and cymoxanil in pepper and soil.

Environ. Monit. Assess. 186(8) , 5307-13, (2014)

A simple and accurate method of determining metalaxyl and cymoxanil in pepper and soil was developed by ultra-performance liquid chromatography-photodiode array detection. The limits of detection were...

Detection of resistance to fungicides, mating types and fitness of Phytophthora infestans in Hebei, China.

Meded. Rijksuniv. Gent. Fak. Landbouwkd. Toegep. Biol. Wet. 67(2) , 307-14, (2002)

In vitro, isolates resistant to metalaxyl (M) and oxadixyl (O) of Phytophthora infestans were 11.2% of 62 isolates from potato and tomato in Hebei Province, mean resistance factor was 15,022 fold and ...

Development of a gas chromatographic method for fungicide cymoxanil analysis in dried hops.

J. Agric. Food Chem. 49(2) , 570-3, (2001)

An analytical method for detecting cymoxanil [2-cyano-N-[(ethylamino)carbonyl]-2-(methoxyimino)acetamide] residues in dried hops was developed utilizing liquid-liquid partitioning, automated gel perme...


More Articles


Related Compounds

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