Uridine monophosphate

Names

[ CAS No. ]:
58-97-9

[ Name ]:
Uridine monophosphate

[Synonym ]:
5'-Uridylic acid
Uridine monophosphate
uridinemonophosphate
4-Hydroxy-1-(5-O-phosphono-β-D-ribofuranosyl)-2(1H)-pyrimidinone
U 5'-P
UMP
Uridylate
2(1H)-Pyrimidinone, 4-hydroxy-1-(5-O-phosphono-β-D-ribofuranosyl)-
Uridine 5'-monophosphate
uridine-5′-monophosphate
uridine 5′-monophosphate
uridinephosphate
Diquafosol Impurity 1
EINECS 200-408-0

Biological Activity

[Description]:

Uridine 5'-monophosphate (5'-Uridylic acid), a monophosphate form of UTP, can be acquired either from a de novo pathway or degradation products of nucleotides and nucleic acids in vivo and is a major nucleotide analogue in mammalian milk[1].

[Related Catalog]:

Research Areas >> Others

[Target]

Human Endogenous Metabolite

[References]

[1]. Li G, et al. Uridine/UMP metabolism and their function on the gut in segregated early weaned piglets. Food Funct. 2019 Jul 17;10(7):4081-4089.

Chemical & Physical Properties

[ Density]:
2.2±0.1 g/cm3

[ Boiling Point ]:
700.1±70.0 °C at 760 mmHg

[ Melting Point ]:
202 ºC (decomp)

[ Molecular Formula ]:
C₉H₁₃N₂O₉P

[ Molecular Weight ]:
324.181

[ Flash Point ]:
377.2±35.7 °C

[ Exact Mass ]:
324.035858

[ PSA ]:
181.12000

[ LogP ]:
-1.80

[ Appearance of Characters ]:
solid

[ Vapour Pressure ]:
0.0±5.0 mmHg at 25°C

[ Index of Refraction ]:
1.754

[ Storage condition ]:
−20°C

[ Water Solubility ]:
H2O: soluble50mg/mL, clear, colorless

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YU8088000

CHEMICAL NAME :: 5'-Uridylic acid

CAS REGISTRY NUMBER :: 58-97-9

BEILSTEIN REFERENCE NO. :: 0047486

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C9-H13-N2-O9-P

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- Volume(issue)/page/year: 60,251,1954

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
YU8088000

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Characterization, antioxidative and ACE inhibitory properties of hydrolysates obtained from thornback ray (Raja clavata) muscle.

J. Proteomics 128 , 458-68, (2015)

Thornback ray muscle hydrolysates (TRMHs) prepared by treatment with proteases from Bacillus subtilis A26 (TRMH-A26), Raja clavata crude alkaline protease extract (TRMH-Crude), Alcalase (TRMH-Alcalase...

Clay catalyzed RNA synthesis under Martian conditions: Application for Mars return samples.

Biochem. Biophys. Res. Commun. 462 , 99-104, (2015)

Catalysis by montmorillonites clay minerals is regarded as a feasible mechanism for the abiotic production and polymerization of key biomolecules on early Earth. We have investigated a montmorillonite...

Pyrimidine homeostasis is accomplished by directed overflow metabolism.

Nature 500(7461) , 237-41, (2013)

Cellular metabolism converts available nutrients into usable energy and biomass precursors. The process is regulated to facilitate efficient nutrient use and metabolic homeostasis. Feedback inhibition...

Related Compounds

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