Ofurace
Names
[ CAS No. ]:
58810-48-3
[ Name ]:
Ofurace
[Synonym ]:
Acetamide, 2-chloro-N-(2,6-dimethylphenyl)-N-(tetrahydro-2-oxo-3-furanyl)-
EINECS 261-451-9
2-chloro-N-(2,6-dimethylphenyl)-N-(tetrahydro-2-oxo-3-furyl)acetamide
2-chloro-2',6'-dimethyl-N-(2-oxo-tetrahydro-3-furanyl)-acetanilide
2-chloro-N-(2,6-dimethylphenyl)-N-(tetrahydro-2-oxo-3-furanyl)acetamide
2-chloro-N-(2,6-dimethylphenyl)-N-(2-oxooxolan-3-yl)acetamide
MFCD01632753
1653655
2-Chloro-N-(2,6-dimethylphenyl)-N-(2-oxotetrahydrofuran-3-yl)acetamide
N-(tetrahydrofuran-2-on-3-yl)-N-(2,6-dimethylphenyl)-2-chloroacetamide
2-Chlor-N-(2,6-dimethylphenyl)-N-(2-oxotetrahydrofuran-3-yl)acetamid
rac-2-chloro-N-(2,6-dimethylphenyl)-N-[(3R)-2-oxooxolan-3-yl]acetamide
2-chloro-N-(2,6-dimethyl-phenyl)-N-(2-oxo-tetrahydro-furan-3-yl)-acetamide
Ofurace [ANSI:BSI:ISO]
(RS)-α-(2-Chloro-N-2,6-xylylacetamido)-γ-butyrolactone
2-Chloro-N-(2,6-dimethylphenyl)-N-(2-oxotetrahydro-3-furanyl)acetamide
Ofurace
Milfuram
2-chloro-N-(2,6-dimethylphenyl)-N-(tetrahydro-2--oxo-3-furanyl)-acetamide
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
482.7±45.0 °C at 760 mmHg
[ Melting Point ]:
145 - 146ºC
[ Molecular Formula ]:
C14H16ClNO3
[ Molecular Weight ]:
281.73
[ Flash Point ]:
245.8±28.7 °C
[ Exact Mass ]:
281.081879
[ PSA ]:
46.61000
[ LogP ]:
0.93
[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C
[ Index of Refraction ]:
1.589
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AE1300200
- CHEMICAL NAME :
- Acetanilide, 2-chloro-2',6'-dimethyl-N-(2-oxotetrahydro-3-furyl)-
- CAS REGISTRY NUMBER :
- 58810-48-3
- BEILSTEIN REFERENCE NO. :
- 1653655
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C14-H16-Cl-N-O3
- MOLECULAR WEIGHT :
- 281.76
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C223,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 35,343,1981
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - domestic
- DOSE/DURATION :
- 5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 35,343,1981
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H319
[ Precautionary Statements ]:
P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36
[ Safety Phrases ]:
S36
[ RIDADR ]:
NONH for all modes of transport
[ RTECS ]:
AE1300200
Articles
Arch. Environ. Contam. Toxicol. 18(6) , 876-80, (1989)
Ofurace, oxadixyl, and alachlor were studied for their effect on hepatic xenobiotic biotransformation in male rats by dosing i.p. with 1 or 100 mg/kg of chemical for 7 days. Ofurace decreased ethoxyre...