4-Chloro-3-methylphenol
Names
[ CAS No. ]:
59-50-7
[ Name ]:
4-Chloro-3-methylphenol
[Synonym ]:
p-Chlorocresol
3-methyl-4-chlorophenol
4-Chloro-m-cresol
4-Chloro-3-cresol
4-chloro-3-methyl phenol
Parol
Phenol, 4-chloro-3-methyl-
Phenol,4-chloro-3-methyl
Baktol
4-CMC
4-Chloro-3-methylphenol
EINECS 200-431-6
QR BG E1
Candaseptic
MFCD00002323
4-CEC
p-Chloro-m-cresol
chlorocresol
4-chlorometa-cresol
4-mpd
Biological Activity
[Description]:
[Related Catalog]:
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
235.0±0.0 °C at 760 mmHg
[ Melting Point ]:
63-65 °C(lit.)
[ Molecular Formula ]:
C7H7ClO
[ Molecular Weight ]:
142.583
[ Flash Point ]:
93.4±21.8 °C
[ Exact Mass ]:
142.018539
[ PSA ]:
20.23000
[ LogP ]:
2.89
[ Vapour Pressure ]:
0.0±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.566
[ Stability ]:
Stable. Incompatible with brass, oxidizing agents, copper, copper alloys.
[ Water Solubility ]:
4 g/L (20 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GO7100000
- CHEMICAL NAME :
- m-Cresol, 4-chloro-
- CAS REGISTRY NUMBER :
- 59-50-7
- BEILSTEIN REFERENCE NO. :
- 1237629
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 15
- MOLECULAR FORMULA :
- C7-H7-Cl-O
- MOLECULAR WEIGHT :
- 142.59
- WISWESSER LINE NOTATION :
- QR DG C
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1830 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 600 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 360 mg/kg
- TOXIC EFFECTS :
- Behavioral - general anesthetic Behavioral - tremor Lungs, Thorax, or Respiration - other changes
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 70 mg/kg
- TOXIC EFFECTS :
- Behavioral - coma Lungs, Thorax, or Respiration - other changes
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 11200 mg/kg/28D-I
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain
MUTATION DATA
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Bacteria - Escherichia coli
- DOSE/DURATION :
- 100 umol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 307,141,1994 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84772 No. of Facilities: 29 (estimated) No. of Industries: 2 No. of Occupations: 12 No. of Employees: 876 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84772 No. of Facilities: 5608 (estimated) No. of Industries: 65 No. of Occupations: 62 No. of Employees: 175929 (estimated) No. of Female Employees: 24335 (estimated)
Safety Information
[ Symbol ]:
GHS05, GHS07, GHS09
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302 + H312-H317-H318-H400
[ Precautionary Statements ]:
P273-P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xn:Harmful
[ Risk Phrases ]:
R21/22;R41;R43;R50
[ Safety Phrases ]:
S26-S36/37/39-S61-S45-S36/37-S16-S7
[ RIDADR ]:
UN 3077 9/PG 3
[ WGK Germany ]:
2
[ RTECS ]:
GO7100000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1(a)
[ HS Code ]:
2908199090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2908199090
[ Summary ]:
HS: 2908199090. derivatives of polyphenols or phenol-alcohols containing only halogen substituents and their salts. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tariff:5.5%. general tariff:30.0%
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