(9S)-Cinchonan-9-ol sulfate (2:1)
Names
[ CAS No. ]:
5949-16-6
[ Name ]:
(9S)-Cinchonan-9-ol sulfate (2:1)
[Synonym ]:
Cinchonan-9-ol, (9S)-, sulfate (2:1) (salt)
(9S)-Cinchonan-9-ol sulfate (2:1)
EINECS 227-708-4
MFCD00035639
cinchonine sulfate
Chemical & Physical Properties
[ Density]:
1.61g/cm3
[ Boiling Point ]:
169 °C(lit.)
[ Melting Point ]:
38-40 °C(lit.)
[ Molecular Formula ]:
C38H46N4O6S
[ Molecular Weight ]:
686.860
[ Flash Point ]:
148 °F
[ Exact Mass ]:
686.313782
[ PSA ]:
155.70000
[ LogP ]:
6.63300
[ Index of Refraction ]:
1.717
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GD3800000
- CAS REGISTRY NUMBER :
- 5949-16-6
- LAST UPDATED :
- 198708
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C19-H22-N2-O.1/2H2-O4-S
- MOLECULAR WEIGHT :
- 343.43
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 78,159,1943
Safety Information
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
26-36
[ RIDADR ]:
1544
[ WGK Germany ]:
3
[ RTECS ]:
GD3800000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)
Articles
Antimicrob. Agents Chemother. 56(10) , 5356-64, (2012)
The Cinchona alkaloids are quinoline aminoalcohols that occur as diastereomer pairs, typified by (-)-quinine and (+)-quinidine. The potency of (+)-isomers is greater than the (-)-isomers in vitro and ...
A theoretical investigation on the Strecker reaction catalyzed by a Ti(IV)-complex catalyst generated from a cinchona alkaloid, achiral substituted 2,2'-biphenol, and tetraisopropyl titanate.Chemistry 19(5) , 1637-46, (2013)
The mechanism and the origin of selectivity of the asymmetric Strecker reaction catalyzed by a Ti(IV)-complex catalyst generated from a cinchona alkaloid, achiral substituted 2,2'-biphenol, and tetrai...
Organocatalytic asymmetric conjugate addition of 3-monosubstituted oxindoles to (E)-1,4-diaryl-2-buten-1,4-diones: a strategy for the indirect enantioselective furanylation and pyrrolylation of 3-alkyloxindoles.Chemistry 18(21) , 6679-87, (2012)
An asymmetric conjugate addition of 3-monosubstituted oxindoles to a range of (E)-1,4-diaryl-2-buten-1,4-diones, catalyzed by commercially available cinchonine, is described. This organocatalytic asym...