1-Anthracenamine
Names
[ CAS No. ]:
610-49-1
[ Name ]:
1-Anthracenamine
[Synonym ]:
EINECS 210-225-8
MFCD00003579
1-AMINOANTHRACENE
Chemical & Physical Properties
[ Density]:
1.208g/cm3
[ Boiling Point ]:
408.2ºC at 760 mmHg
[ Melting Point ]:
114-118 °C(lit.)
[ Molecular Formula ]:
C14H11N
[ Molecular Weight ]:
193.24400
[ Flash Point ]:
224.4ºC
[ Exact Mass ]:
193.08900
[ PSA ]:
26.02000
[ LogP ]:
4.15640
[ Index of Refraction ]:
1.765
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CA9100000
- CHEMICAL NAME :
- 1-Anthracenamine
- CAS REGISTRY NUMBER :
- 610-49-1
- BEILSTEIN REFERENCE NO. :
- 2209406
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 13
- MOLECULAR FORMULA :
- C14-H11-N
- MOLECULAR WEIGHT :
- 193.26
- WISWESSER LINE NOTATION :
- L C666J DZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 7200 mg/kg/27D-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors
- TYPE OF TEST :
- DNA repair
MUTATION DATA
- TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Rodent - mouse Lymphocyte
- DOSE/DURATION :
- 10200 nmol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 203,155,1988
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
CA9100000
[ HS Code ]:
2921499090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2921499090
[ Summary ]:
2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
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Aim/Materials and Methods: In order to develop better drugs against non-small cell lung cancer (NSCLC), we screened a variety of compounds and treated the human lung adenocarcinoma cell line A549 with...
Stereoselectivity of isoflurane in adhesion molecule leukocyte function-associated antigen-1.PLoS ONE 9(5) , e96649, (2014)
Isoflurane in clinical use is a racemate of S- and R-isoflurane. Previous studies have demonstrated that the effects of S-isoflurane on relevant anesthetic targets might be modestly stronger (less tha...
Biopartitioning micellar chromatography to predict mutagenicity of aromatic amines.Eur. J. Med. Chem. 42 , 1396-402, (2007)
Mutagenicity is a toxicity endpoint associated with the chronic exposure to chemicals. Aromatic amines have considerable industrial and environmental importance due to their widespread use in industry...