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2,5-diaminotoluenesulfate

Names

[ CAS No. ]:
615-50-9

[ Name ]:
2,5-diaminotoluenesulfate

[Synonym ]:
P-TOLYLENEDIAMINE SULFATE
2,5-Diaminotoluene sulfate
2,5-Diaminotoluene s
p-Toluenediamine sulphate
2,5-diaminotoluenesulfate
TOLUENEDIAMINESULFATE
2-methyl-para-phenylenediamine sulfate
EINECS 210-431-8
2,5-Diaminotoluene sulphate
JAROCOL TDS
p-toluenediaminesulphate
2-Methyl-1,4-benzenediamine sulfate (1:1)
p-diaminotoluenesulfate
1,4-Benzenediamine, 2-methyl-, sulfate (1:1)
MFCD00013003
2-Methylbenzene-1,4-diaminium sulfate
2-Methyl-p-phenylenediamine sulphate
2-Methyl-p-phenylendiamin,Sulfat
2,4-DICHLORO-6-PICOLINE
2-methyl-p-phenylenediamine,sulfate
5-DiaMinotoluene Sulfate
2,5-diaminotoluene sulfuric acid salt
2-Methylbenzene-1,4-diamine sulfate (1:1)
ZR DZ B1 &&H2SO4
p-toluylenediaminesulphate
p-tolylenediaminesulphate
2,5-Toluenediamine Sulfate

Chemical & Physical Properties

[ Boiling Point ]:
273.7ºC at 760 mmHg

[ Melting Point ]:
>300 °C(lit.)

[ Molecular Formula ]:
C7H12N2O4S

[ Molecular Weight ]:
220.246

[ Exact Mass ]:
220.051773

[ PSA ]:
135.02000

[ LogP ]:
2.74980

[ Water Solubility ]:
soluble

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XT0525000
CAS REGISTRY NUMBER :
615-50-9
LAST UPDATED :
199710
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C7-H10-N2.H2-O4-S
MOLECULAR WEIGHT :
220.27
WISWESSER LINE NOTATION :
ZR DZ B1 &S-O4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
98 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
49 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
250 ug/plate
REFERENCE :
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 71,293,1983 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2324 No. of Facilities: 2288 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 21487 (estimated) No. of Female Employees: 16214 (estimated)

Safety Information

[ Symbol ]:

GHS06, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H312 + H332-H317-H411

[ Precautionary Statements ]:
P273-P280-P301 + P310

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T:Toxic

[ Risk Phrases ]:
R20/21;R25;R43;R51/53

[ Safety Phrases ]:
S24-S37-S45-S61

[ RIDADR ]:
UN 2811 6.1/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
XT0525000

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1

[ HS Code ]:
2921519090

Customs

[ HS Code ]: 2921519090

[ Summary ]:
2921519090. o-, m-, p-phenylenediamine, diaminotoluenes, and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:17.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Effect of 4 toluene diamine isomers on murine testicular DNA synthesis.

Mutat. Res. 91(1) , 75-9, (1981)

Final amended report of the safety assessment of toluene-2,5-diamine, toluene-2,5-diamine sulfate, and toluene-3,4-diamine as used in cosmetics.

Int. J. Toxicol. 29(3 Suppl) , 61S-83S, (2010)

Toluene-2,5-diamine, toluene-2,5-diamine sulfate, and toluene-3,4-diamine are diaminotoluenes used as colorants in permanent hair dyes and tints. Toluene-2,5-diamine is used in 79 products at concentr...

Occupational asthma, rhinitis, and contact urticaria caused by oxidative hair dyes in hairdressers.

Ann. Allergy Asthma Immunol. 112(1) , 46-52, (2014)

Oxidative hair dyes commonly contain paraphenylene diamine (PPD) and its derivatives, a well-known cause of delayed hypersensitivity among both consumers and hairdressers. They are also considered pos...


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