2-Propyn-1-yl 4-methylbenzenesulfonate
Names
[ CAS No. ]:
6165-76-0
[ Name ]:
2-Propyn-1-yl 4-methylbenzenesulfonate
[Synonym ]:
MFCD00078365
2-Propyn-1-ol, 4-methylbenzenesulfonate
prop-2-ynyl 4-methylbenzenesulfonate
2-Propyn-1-yl 4-methylbenzenesulfonate
Prop-2-yn-1-yl 4-methylbenzenesulfonate
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
345.8±17.0 °C at 760 mmHg
[ Molecular Formula ]:
C10H10O3S
[ Molecular Weight ]:
210.250
[ Flash Point ]:
163.0±20.9 °C
[ Exact Mass ]:
210.035065
[ PSA ]:
51.75000
[ LogP ]:
1.68
[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C
[ Index of Refraction ]:
1.541
[ Storage condition ]:
2-8°C
[ Water Solubility ]:
Soluble in Chloroform, Dichloromethane, DMSO, Ethyl Acetate. Not miscible in water.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XT7300000
- CHEMICAL NAME :
- p-Toluenesulfonic acid, 2-propynyl ester
- CAS REGISTRY NUMBER :
- 6165-76-0
- BEILSTEIN REFERENCE NO. :
- 1912957
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C10-H10-O3-S
- MOLECULAR WEIGHT :
- 210.26
- WISWESSER LINE NOTATION :
- 1UU2OSWR D1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 180 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00017
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R22;R36/37/38
[ Safety Phrases ]:
S26-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
XT7300000
[ HS Code ]:
2905290000
Synthetic Route
Customs
[ HS Code ]: 2905290000
[ Summary ]:
2905290000 unsaturated monohydric alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%
Articles
J. Pharmacol. Sci. 125(2) , 157-68, (2014)
The functional activation of Gi/o proteins coupled to muscarinic acetylcholine receptors (mAChRs) was investigated with the conventional guanosine-5'-O-(3-[(35)S]thio) triphosphate ([(35)S]GTPγS) bind...