1,4-Bis(chloromethyl)benzene

Names

[ CAS No. ]:
623-25-6

[ Name ]:
1,4-Bis(chloromethyl)benzene

[Synonym ]:
MFCD00000920
G1R D1G
1,4-Bis(chloromethyl)-benzene
1,4-Bis(chloromethyl)benzene
EINECS 210-782-7
Benzene, 1,4-bis(chloromethyl)-

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
242.5±0.0 °C at 760 mmHg

[ Melting Point ]:
98-101 °C(lit.)

[ Molecular Formula ]:
C₈H₈Cl₂

[ Molecular Weight ]:
175.055

[ Flash Point ]:
119.2±15.1 °C

[ Exact Mass ]:
174.000305

[ LogP ]:
2.76

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.545

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
hydrolysis

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ZE4100000

CHEMICAL NAME :: p-Xylene, alpha,alpha'-dichloro-

CAS REGISTRY NUMBER :: 623-25-6

BEILSTEIN REFERENCE NO. :: 0774706

LAST UPDATED :: 199712

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C8-H8-Cl2

MOLECULAR WEIGHT :: 175.06

WISWESSER LINE NOTATION :: G1R D1G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1280 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Gastrointestinal - hypermotility, diarrhea

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 501 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Liver - other changes

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 100 ug/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 191,79,1987

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H410

[ Precautionary Statements ]:
P273-P305 + P351 + P338-P501

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
T+:Verytoxic;

[ Risk Phrases ]:
R22;R26;R36/37/38

[ Safety Phrases ]:
S26-S36/37-S45-S36/37/39-S28A

[ RIDADR ]:
3261

[ WGK Germany ]:
3

[ RTECS ]:
ZE4100000

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1

[ HS Code ]:
29036990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2903999090

[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Effects of quaternization on the morphological stability and antibacterial activity of electrospun poly(DMAEMA-co-AMA) nanofibers.

Colloids Surf. B Biointerfaces 133 , 148-55, (2015)

Electrospun nanofibers with antibacterial activity are greatly promising for medical treatment and water purification. Herein we report antibacterial nanofibers electrospun from a series of poly(dimet...

Contact dermatitis caused by "chloromethyl heterocyclic intermediates".

Contact Dermatitis 16(1) , 52, (1987)

Preparation of PPV nanotubes and nanorods and carbonized products derived therefrom. Kim K and Jin J.

Nano Lett. 1(11) , 205-210, (1981)

Related Compounds

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