<Suppliers Price>

Dehydronifedipine

Names

[ CAS No. ]:
67035-22-7

[ Name ]:
Dehydronifedipine

[Synonym ]:
dimethyl 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate
Dehydronifedipine
B 4759
Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate
Nifedipine Impurity 1

Chemical & Physical Properties

[ Density]:
1.284g/cm3

[ Boiling Point ]:
443.7ºC at 760 mmHg

[ Melting Point ]:
100-105ºC

[ Molecular Formula ]:
C17H16N2O6

[ Molecular Weight ]:
344.31900

[ Flash Point ]:
222.1ºC

[ Exact Mass ]:
344.10100

[ PSA ]:
111.31000

[ LogP ]:
3.37000

[ Appearance of Characters ]:
powder | yellow

[ Index of Refraction ]:
1.575

[ Storage condition ]:
2-8°C

MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H318

[ Precautionary Statements ]:
P280-P305 + P351 + P338 + P310

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
41

[ Safety Phrases ]:
26-39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

Synthetic Route

Precursor & DownStream

Articles

Nuclear translocation of nuclear transcription factor-kappa B by alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors leads to transcription of p53 and cell death in dopaminergic neurons.

Mol. Pharmacol. 63(4) , 784-90, (2003)

We describe a new molecular mechanism of cell death by excitotoxicity mediated through nuclear transcription factor kappa B (NF kappa B) in rat embryonic cultures of dopaminergic neurons. Treatment of...

Enhancement of CYP3A4 activity in Hep G2 cells by lentiviral transfection of hepatocyte nuclear factor-1 alpha.

PLoS ONE 9(4) , e94885, (2014)

Human hepatoma cell lines are commonly used as alternatives to primary hepatocytes for the study of drug metabolism in vitro. However, the phase I cytochrome P450 (CYP) enzyme activities in these cell...

Interactions of endosulfan and methoxychlor involving CYP3A4 and CYP2B6 in human HepaRG cells.

Drug Metab. Dispos. 42(8) , 1235-40, (2014)

Humans are usually exposed to several pesticides simultaneously; consequently, combined actions between pesticides themselves or between pesticides and other chemicals need to be addressed in the risk...


More Articles


Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.